Fear of cancer recurrence across the survivorship trajectory: Results from a survey of adult long-term cancer survivors
Fear of cancer recurrence across the survivorship trajectory: Results from a survey of adult long-term cancer survivors
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DOI：
10.1002/pon.5188
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发表时间：
2019-08-15
期刊：
影响因子：
3.6
通讯作者：
Mehnert-Theuerkauf, Anja
中科院分区：
文献类型：
--
作者：
Goetze, Heide;Taubenheim, Sabine;Mehnert-Theuerkauf, Anja
目的 我们的研究分析了长期癌症幸存者对癌症复发的恐惧与医疗变量、抑郁、焦虑和生活质量的关系。方法 我们提供了从 1,002 名癌症幸存者（53% 男性，平均年龄 = 68 岁，26% 前列腺癌，22% 乳腺癌）诊断后所有癌症类型 5 (N=660) 和 10 (N=342) 中获得的数据，这些幸存者是通过德国大型临床癌症登记处招募的一项横断面研究。使用经过验证的自我报告问卷（12 项简版恐惧进展问卷 [FoP-Q-SF]、患者健康问卷 9 [PHQ-9[ 和一般性焦虑症 7 [GAD-7]）测量 FoR、抑郁和焦虑。以 FoR 作为因变量，自诊断以来的时间作为控制变量，建立分层回归模型。结果 我们发现 17% 的癌症幸存者具有高 FoR 值（FoP-Q-SF 总分>33）。 5 年队列中的 FoR 较高（P=.028，d=0.153）。癌症幸存者最担心的是家庭的未来；他们表示在预约医生之前会感到紧张，并且害怕依赖陌生人的帮助。较高的 FoR 与女性相关（Beta=.149，P
Objective Our study analysed fear of cancer recurrence (FoR) in long-term cancer survivors in relation to medical variables, depression, anxiety, and quality of life. Methods We present data obtained from 1,002 cancer survivors (53% male, mean age=68 years, 26% prostate cancer, 22% breast cancer) across all cancer types 5 (N=660) and 10 (N=342) years after diagnosis, who were recruited via a large Clinical Cancer Registry in Germany in a cross-sectional study. FoR, depression, and anxiety were measured using validated self-report questionnaires (12-item short version of the Fear of Progression Questionnaire [FoP-Q-SF], Patient Health Questionnaire-9 [PHQ-9[, and General Anxiety Disorder-7 [GAD-7]). Hierarchical regression models were carried out with FoR as dependent variable and time since diagnosis as control variable. Results We found high FoR-values in 17% of the cancer survivors (FoP-Q-SF total score>33). FoR was higher in the 5-year cohort (P=.028, d=0.153). Cancer survivors were most worried about the future of the family; they report being nervous prior to doctor's appointment and being afraid of relying on strangers help. Higher FoR was related to female gender (Beta=.149, P