Pulmonary alveolar proteinosis induced by hydrofluoric acid exposure during fire extinguisher testing
Pulmonary alveolar proteinosis induced by hydrofluoric acid exposure during fire extinguisher testing
复制标题
灭火器试验过程中暴露于氢氟酸引起的肺泡蛋白沉着症
DOI：
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发表时间：
2015
影响因子：
3
通讯作者：
S. Jeong
中科院分区：
文献类型：
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作者：
Yujin Kim;J. Shin;S. Kang;S. Kyung;Jeong;Sang;SangMin Lee;S. Jeong
前言自动灭火系统使用氢氟烃(HF)来化学灭火。在高温下，HF可释放出一种有毒的、潜在致命的气体氢氟酸(HFA)。病例报告：一位52岁的男性患者因持续8个月的呼吸困难来到我们的肺科就诊。他一直在一家生产灭火器的工厂工作。进行支气管镜检查，并从右下叶取肺活检。确诊为肺泡蛋白沉积症(PAP)后，行全肺灌洗。在本例中，灭火器气体引起了肺泡蛋白沉积症。这种材料应该小心使用并进一步研究。讨论HFA具有腐蚀性，可以穿透有机材料，包括身体组织。根据暴露方式的不同，可能会导致皮肤溃疡、肺损伤，甚至全身休克。这份报告描述了在长期、反复接触灭火器喷雾后出现的PAP。氢氟酸可引起肺部疾病，如PAP。
IntroductionAutomatic fire suppression systems use hydrofluorocarbons (HF) to extinguish fires chemically. At high temperatures, HF can release hydrofluoric acid (HFA), a toxic, potentially lethal gas.Case reportA 52-year-old male visited our Pulmonary Division with dyspnea of 8-months duration. He had been working at a facility that manufactured fire extinguishers. Bronchoscopy was performed and a transbronchial lung biopsy was taken from the right lower lobe. After the patient was diagnosed with pulmonary alveolar proteinosis (PAP), whole-lung lavage was performed. In this case, fire extinguisher gas induced pulmonary alveolar proteinosis. This material should be used with care and investigated further.DiscussionHFA is corrosive and penetrates organic materials, including body tissues. Depending on the mode of exposure, skin ulceration, pulmonary injury, or even systemic shock can result. This report describes PAP that developed after chronic, repeated exposure to fire extinguisher spray. Hydrofluoric acid can induce pulmonary disorders such as PAP.