Population genetic structure of the malaria vector Anopheles moucheti in south Cameroon forest region
Population genetic structure of the malaria vector Anopheles moucheti in south Cameroon forest region
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DOI：
10.1016/j.actatropica.2006.12.004
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发表时间：
2007-01-01
期刊：
影响因子：
2.7
通讯作者：
Simard, Frederic
中科院分区：
文献类型：
--
作者：
Antonio-Nkondjio, Christophe;Ndo, Cyrille;Simard, Frederic
我们使用最近开发的微卫星DNA标记来探索疟疾媒介——摩氏按蚊的种群遗传结构。对10个位点的多态性进行了检测，以评估来自南喀麦隆、相距65-400公里的4个鼠伊蚊种群之间的遗传分化水平。所有的微卫星位点都具有高度的多态性，每个位点有9 ~ 17个不同的等位基因。F-st估计范围为0.0094 ~ 0.0275 （P < 0.001）。这些结果表明，moucheti种群之间的遗传分化水平非常低。最近获得的微卫星位点揭示了评估喀麦隆穆氏伊蚊地理种群间遗传分化的有用标记。(c) 2006 Elsevier B.V.版权所有
We used recently developed microsatellite DNA markers to explore the population genetic structure of the malaria vector, Anopheles moucheti. Polymorphism at 10 loci was examined to assess level of genetic differentiation between four A. moucheti populations from South Cameroon situated 65-400km apart. All microsatellite loci were highly polymorphic with a number of distinct alleles per locus ranging from 9 to 17. F-st estimates ranging from 0.0094 to 0.0275 (P < 0.001) were recorded. These results suggest a very low level of genetic differentiation between A. moucheti populations. The recently available microsatellite loci revealed useful markers to assess genetic differentiation between geographical populations of A. moucheti in Cameroon. (c) 2006 Elsevier B.V. All rights reserved.