Natural products : discourse, diversity and design
Natural products : discourse, diversity and design
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发表时间：
2014
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通讯作者：
A. Osbourn;R. Goss;G. Carter
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作者：
A. Osbourn;R. Goss;G. Carter
天然产物：话语，多样性和设计提供了基因组时代天然产物领域发现的信息和可访问的概述，汇集了各个王国的进展。随着基因组学数据越来越清楚地表明，微生物和植物的基因组中包含的天然产物合成基因远远多于先前鉴定的代谢物数量所预测的，这些生物合成多种天然产物的潜力可能远远大于先前设想的。《天然产物》不仅探讨了这些代谢物的自然作用的哲学问题，还探讨了单途径和多途径的进化，以及如何利用这些途径和产物来帮助发现新的生物活性物质和作用方式。
Natural Products: Discourse, Diversity and Design provides an informative and accessible overview of discoveries in the area of natural products in the genomic era, bringing together advances across the kingdoms. As genomics data makes it increasingly clear that the genomes of microbes and plants contain far more genes for natural product synthesis than had been predicted from the numbers of previously identified metabolites, the potential of these organisms to synthesize diverse natural products is likely to be far greater than previously envisaged. Natural Products addresses not only the philosophical questions of the natural role of these metabolites, but also the evolution of single and multiple pathways, and how these pathways and products may be harnessed to aid discovery of new bioactives and modes of action.