Global transcriptome analysis of Staphylococcus aureus response to hydrogen peroxide
Global transcriptome analysis of Staphylococcus aureus response to hydrogen peroxide
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DOI：
10.1128/jb.188.4.1648-1659.2006
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发表时间：
2006-02-01
影响因子：
3.2
通讯作者：
Bentley, WE
中科院分区：
文献类型：
--
作者：
Chang, W;Small, DA;Bentley, WE
金黄色葡萄球菌反应与保护策略对抗吞噬细胞衍生的活性氧化剂感染人类。在此，我们报告了金黄色葡萄球菌对过氧化氢诱导的氧化应激的细胞反应的转录组分析。数据表明，氧化反应包括诱导参与毒力，DNA修复，特别是厌氧代谢的基因。
Staphylococcus aureus responds with protective strategies against phagocyte-derived reactive oxidants to infect humans. Herein, we report the transcriptome analysis of the cellular response of S. aureus to hydrogen peroxide-induced oxidative stress. The data indicate that the oxidative response includes the induction of genes involved in virulence, DNA repair, and notably, anaerobic metabolism.