ELECTRON MICROSCPY OF POSTERIOR POLYMORPHOUS DEGENERATION
ELECTRON MICROSCPY OF POSTERIOR POLYMORPHOUS DEGENERATION
复制标题
DOI：
10.1016/0002-9394(71)91683-7
复制
发表时间：
1971-01-01
影响因子：
4.2
通讯作者：
KUWABARA, T
中科院分区：
文献类型：
--
作者：
BORUCHOFF, SA;KUWABARA, T
7).微绒毛比正常浅层上皮皱襞高 111 0，角膜大小不规则。侧向 ccl1 memlrrnnes 由许多具有突出的张力原纤维附着的桥粒~~~连接（t；图 7），在所有末端未发现紧密连接。细胞质有相对电子化的基质，可见丰富的角原纤维。原纤维形成不同尺寸的束。 hlicl-c，组织；粒细胞极其稀疏。？\粒粒体。内质网和高尔基体在细胞质中缺失或完全缺失。 011l\沿着角原纤维看到少量糖原颗粒。偶尔的细胞，特别是在聚集区域，较大并含有包涵体，这些包涵体可能是噬菌体（图8）。在前房的小细胞和瓦斯特罗姆之间形成了约30°的厚的描述物mcmhr：〜ne（图5）。它由一个薄的（3~）门廊组成，它很高？ PAS-阳性光显微镜1) i~~~~ ly位于前部界限和厚的(I.<-,%~) la!.(, r异常胶原纤维\在后部区域具有最小的粘蛋白含量。Decrmet膜的thill Irortion厚度为ulli TOI-m，由粗颗粒物质组成，在巩膜中形成100 nm间距。膜的精细结构外观与人工角膜后弹力层后部的结构相同，异常的胶原层由不规则的细纤维层、短胶原填充物和基底层物质组成（图5和9）。t11细胞下方形成厚的基底膜。纤维状物质形成两种01波德结构。其中一种是制成的。聚集的短原纤维具有 100 nm 的空间，另一个由较长的 (1-3~) fihril< 具有 30 mm 的空间形成
7). The microvilli were taller 111an the plicae of tllc normal superficial cpitheliulll 0i the cornea alit1 were lrrcgular ill size. Lateral ccl1 memlrrnnes were joined by numerous desmoson~~~ s which had prominent tonofibril attachments(t; ig. 7) No tight junctions were found at tile allical ends. The cytoplasm had a relatively electron tlcnsv matrix iti which keratofibrils were seen abundantl>. The fibrils formed bundles of varyill!: sizes. hlicl-c, org; ltlclles were cxtremely sparse.?\litochondria. endoplasmic reticulum and Golgi apparatus wcrv t-are or entirely missing from the cytoplasm. 011l\a small number of glycogen particles was seen anlong the keratofibrils. Occasional cells, especially in t lie area of the clumping-s, were larger and contained inclusion bodies, which presumably were phag~ q&ed tlehris c Fig. 8).A thick Descrmct’s mcmhr:~ ne measuring about 30~ had formed between the litling cell of the anterior chamber and tile stromn(Fig. 5). This consisted of a thin (3~) porticul which was highl? PAS-positi\-e light microsco1) i~~~~ lly at the anterior limit and a thick (I.<-,%~) la!.(, r of abnormal collagen fibers\vith a minimal mucoprotein content in the posterior region. The thill Irortion of the Descrmet’s membrane was ulli TOI-m in thickness and consisted of coarse grancllal-substances which formed 100 nm spacings in sc\. eral locations(Fig. 9). The fine structural appearance of the membrane was identical to that of the atlterior portion of the Descemet’s membrane of an arltllt cornea. The abnormal collagen layer consistvtl of irregular layers of fine fibrils, short collagen fillers and basal lamina substance(Figs. 5 and 9).-4 thick basement membrane was formed beneath t11 (, cells. The fibrillar substance formed two kinds 01 bauded structures. One was made of aggregated short fibrils with a handing of 100 nm spaces, and the other was formed of longer (1-3~) fihril< with 30 mm spac-