Incidence of acute kidney injury among patients with chronic kidney disease: a single-center retrospective database analysis
Incidence of acute kidney injury among patients with chronic kidney disease: a single-center retrospective database analysis
复制标题
DOI：
10.1007/s10157-016-1243-2
复制
发表时间：
2017-02-01
影响因子：
2.3
通讯作者：
Okuhara, Yoshiyasu
中科院分区：
文献类型：
--
作者：
Hatakeyama, Yutaka;Horino, Taro;Okuhara, Yoshiyasu
背景急性肾损伤（AKI）是住院患者的一种严重并发症，与慢性肾脏疾病（CKD）密切相关。方法回顾性队列研究1981-2011年高知医学院医院CKD分期AKI发生率。AKI的定义和分期根据肾脏疾病改善的全球结局标准，使用血清肌酐水平。结果：我们分析了122,653名日本患者（57105名男性，46.6%）的数据。AKI的发生率为7.8%（95%可信区间为7.7- 8.0%）。与非AKI患者相比，1-2期AKI患者更可能是男性。1-2期AKI患者明显比非AKI或3期AKI患者年龄大。在肾小球滤过率为C90、60-89、45-59、30-44、15-29和C90的人群中，AKI的发生率分别为6.7、5.9、10.4、18.4%、30.0%和48.8%
Background Acute kidney injury (AKI) is a serious complication among hospitalized individuals and is closely associated with chronic kidney disease (CKD).Methods This retrospective cohort study evaluated the incidences of AKI according to CKD stage at Kochi Medical School hospital during 1981-2011. AKI was defined and staged according to the kidney disease improving global outcomes criteria, using serum creatinine levels.Results We analyzed data from 122,653 Japanese patients (57,105 men, 46.6 %). The incidence of AKI was 7.8 % (95 % confidence interval 7.7-8.0 %). Compared to nonAKI patients, patients with stage 1-2 AKI were more likely to be men. Patients with stage 1-2 AKI were significantly older than non-AKI or stage 3 AKI patients. The incidences of AKI were 6.7, 5.9, 10.4, 18.4, 30.0, and 48.8 % among individuals with estimated glomerular filtration rates of C90, 60-89, 45-59, 30-44, 15-29, and