Serum ferritin and transferrin saturation in Asians and pacific islanders
Serum ferritin and transferrin saturation in Asians and pacific islanders
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DOI:
10.1001/archinte.167.7.722
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发表时间:
2007-04-09
影响因子:
--
通讯作者:
Adams, Paul C.
中科院分区:
文献类型:
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作者:
Harris, Emily L.;McLaren, Christine E.;Adams, Paul C.
Background: Asians and Pacific Islanders in the Hemochromatosis and Iron Overload Screening (HEIRS) Study had the highest prevalence of elevated serum ferritin (SF) and transferrin saturation (TS) levels, but to our knowledge, the reasons for this have not been investigated.Methods: Using multiple linear regression, we compared TS and SF distributions for 42 720 Asian, Pacific Islander, and white HEIRS Study participants recruited through 5 field centers in North America who did not have HFE C282Y or H63D alleles.Results: Compared with their white counterparts, Asian men had a 69-ng/mL (155-pmol/L) higher adjusted mean SF level and a 3% higher TS level (P