Serum ferritin and transferrin saturation in Asians and pacific islanders

Serum ferritin and transferrin saturation in Asians and pacific islanders
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DOI:
10.1001/archinte.167.7.722
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发表时间:
2007-04-09
影响因子:
--
通讯作者:
Adams, Paul C.
Adams, Paul C.
中科院分区:
其他
文献类型:
--
作者:
Harris, Emily L.;McLaren, Christine E.;Adams, Paul C.

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背景资料:在血色病和铁超负荷筛查(HEIRS)研究中,亚洲人和太平洋岛民血清铁蛋白(SF)和转铁蛋白饱和度(TS)水平升高的患病率最高,但据我们所知,其原因尚未调查。方法:使用多元线性回归,我们比较了42720名亚洲人,太平洋岛民,结果:与白色男性相比,亚洲男性校正后的SF水平高69 ng/mL(155 pmol/L),TS水平高3%(P
Background: Asians and Pacific Islanders in the Hemochromatosis and Iron Overload Screening (HEIRS) Study had the highest prevalence of elevated serum ferritin (SF) and transferrin saturation (TS) levels, but to our knowledge, the reasons for this have not been investigated.Methods: Using multiple linear regression, we compared TS and SF distributions for 42 720 Asian, Pacific Islander, and white HEIRS Study participants recruited through 5 field centers in North America who did not have HFE C282Y or H63D alleles.Results: Compared with their white counterparts, Asian men had a 69-ng/mL (155-pmol/L) higher adjusted mean SF level and a 3% higher TS level (P