Differential effects of UPPS-P impulsivity on subjective alcohol response and craving: An experimental test of acquired preparedness.

Differential effects of UPPS-P impulsivity on subjective alcohol response and craving: An experimental test of acquired preparedness.
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UPPS-P 冲动对主观酒精反应和渴望的不同影响:后天准备的实验测试。

DOI:
10.1037/pha0000524
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发表时间:
2023
影响因子:
2.3
通讯作者:
Leeman,RobertF
Leeman,RobertF
中科院分区:
医学3区
文献类型:
--
作者:
Waddell,JackT;Corbin,WilliamR;Leeman,RobertF

文献摘要

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最近的研究将获得性准备模型扩展到实验数据,发现冲动性预测主观酒精反应,这是一种与预期相关但不同的结构。然而,研究还没有测试冲动性的具体方面是否能预测主观反应,或者冲动性是否能通过主观反应间接预测酒精渴望。报告过去一个月酗酒的年轻人(N= 448)参加了一项安慰剂控制的酒精管理研究。中介模型测试了UPPS-P冲动性方面是否通过对血液酒精含量(BAC)的上升和下降肢的主观反应间接预测酒精渴望。高唤醒的积极(如社交)、低唤醒的积极(如放松)、高唤醒的消极(如粗鲁)和低唤醒的消极(如头晕)的主观效应在四肢上被测量。没有检测到饮料条件的调节作用,因此模型在饮料条件下崩溃。感觉寻求通过四肢的高唤醒积极主观反应间接预测渴望,而积极和消极紧急直接预测渴望。在控制了主观反应和渴望的基线后,感觉寻求和消极紧迫感对主观反应和渴望的影响变得不显著。积极急迫性对渴望的影响仍然存在,积极急迫性对高觉醒的影响也出现在上升肢体上。研究结果表明,冲动、主观反应和渴望之间的关系取决于冲动的具体方面。针对饮酒前提示暴露和/或积极情绪的干预措施可能对感觉寻求者最有效,而针对主观反应和/或期望的干预措施可能对积极紧迫感高的个体最有效。
Recent studies have extended the acquired preparedness model to experimental data, finding that impulsivity predicts subjective alcohol response, a related yet distinct construct from expectancies. However, studies have not tested whether specific facets of impulsivity predict subjective response, or whether impulsivity indirectly predicts alcohol craving through subjective response. Young adults who reported past-month binge drinking (N= 448) participated in a placebo-controlled alcohol administration study. Mediation models tested whether UPPS-P impulsivity facets indirectly predicted alcohol craving through subjective response on the ascending and descending limbs of the blood alcohol content (BAC). High arousal positive (eg, sociable), low arousal positive (eg, relaxed), high arousal negative (eg, rude), and low arousal negative (eg, dizzy) subjective effects were measured across limbs. Moderation by beverage condition was not detected, so models were collapsed across beverage condition. Sensation seeking indirectly predicted craving through high arousal positive subjective response on both limbs, whereas positive and negative urgency directly predicted craving. When controlling for baseline subjective response and craving, effects of sensation seeking and negative urgency on subjective response and craving became nonsignificant. The effects of positive urgency on craving remained, and an effect of positive urgency on high arousal positive effects emerged on the ascending limb. Findings suggest that relations among impulsivity, subjective response, and craving are contingent upon the specific facet of impulsivity. Interventions targeting predrink cue exposure and/or positive emotionality may be most effective for sensation seekers, whereas targeting subjective response and/or expectancies may be most efficacious for individuals high in positive urgency.