Shear-induced microstructures and dynamics processes of phospholipid cylinders in solutions
Shear-induced microstructures and dynamics processes of phospholipid cylinders in solutions
复制标题
溶液中磷脂柱的剪切诱导微观结构和动力学过程
DOI：
10.1038/s41598-019-51933-z
复制
发表时间：
2019
影响因子：
4.6
通讯作者：
Li Shiben
中科院分区：
文献类型：
--
作者：
Shan Yue;Qiang Xiaowei;Ye Jianzhu;Wang Xianghong;He Linli;Li Shiben
采用耗散粒子动力学模拟方法研究了磷脂圆柱体在水溶液中剪切诱导的微观结构及其动力学过程。本文选取在无剪切流动条件下形成的各种截面的磷脂圆柱体，研究剪切流动对其结构和动力学过程的影响。剪切流诱导从圆柱体到囊泡的过渡在弱速率和过渡到囊泡片层混合物与剪切速率增加和片层结构在强剪切速率。详细讨论了动态过程中高分子链的平均回转半径和形状因子。结果表明，剪切流动使高分子链的结构沿剪切方向沿着伸长，在强剪切作用下，高分子链的构型可迅速转变为椭球体结构。
Shear-induced microstructures and their corresponding dynamic processes are investigated for phospholipid cylinders in aqueous solution by dissipative particle dynamic simulation. Various phospholipid cylinders with cross-sections, which are formed under shear-free flow, are selected to examine the effects of shear flow on their structures and dynamic processes. Shear flow induces the transition from cylinders into vesicles at weak rate and the transition into vesicle–lamella mixtures with increased shear rate and lamella structures at the strong shear rate. Then, the average radius of gyration and shape factors of the polymer chains in the dynamic processes are discussed in detail. Results show that shear flow causes the structure of the polymer chains to be elongated along the shear direction, and the configuration of the polymer chain can be rapidly transformed into an ellipsoid structure under strong shear.