POPULATION RESPONSE CHARACTERISTICS OF INTRINSIC SIGNALS IN THE CAT SOMATOSENSORY CORTEX FOLLOWING CANINE MECHANICAL STIMULATION
POPULATION RESPONSE CHARACTERISTICS OF INTRINSIC SIGNALS IN THE CAT SOMATOSENSORY CORTEX FOLLOWING CANINE MECHANICAL STIMULATION
复制标题
犬机械刺激后猫体感皮层内在信号的群体反应特征
DOI：
10.1016/j.neuroscience.2016.04.052
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发表时间：
2016
期刊：
影响因子：
3.3
通讯作者：
Yu Hongbo
中科院分区：
文献类型：
--
作者：
Tao Jianxiang;Wang Jian;Li Zhong;Meng Jianjun;Yu Hongbo
内源性信号光学成像技术因其具有较高的空间分辨率和灵敏度而被广泛应用于各种感觉皮层的功能图测量。然而，这项技术在牙科中的应用还没有报道。在这项研究中，内在信号光学成像被用来调查机械驱动的反应，在猫的躯体感觉皮层，当点状机械刺激施加到上颌犬齿。得到了全局信号及其空间组织模式。全局信号强度随着刺激强度逐渐增加。对侧和同侧机械刺激的反应强度无显著差异。记录在乙状回比冠状回的反应略大。猫的躯体感觉皮层由来自犬的机械刺激的感觉输入激活，缺乏地形和功能组织。它没有被组织成表示来自每个牙齿或刺激方向的感觉输入的列。这些结果表明，内在信号光学成像是一个有效的工具，调查神经反应和神经可塑性的躯体感觉皮层，代表牙齿。
Intrinsic signal optical imaging has been widely used to measure functional maps in various sensory cortices due to better spatial resolution and sensitivity for detecting cortical neuroplasticity. However, application of this technique in dentistry has not been reported. In this study, intrinsic signal optical imaging was used to investigate mechanically driven responses in the cat somatosensory cortex, when punctate mechanical stimuli were applied to maxillary canines. The global signal and its spatial organization pattern were obtained. Global signal strength gradually increased with stimulus strength. There was no significant difference in response strength between contralateral and ipsilateral mechanical stimulation. A slightly greater response was recorded in the sigmoidal gyrus than in the coronal gyrus. The cat somatosensory cortex activated by sensory inputs from mechanical stimulation of canines lacks both topographical and functional organization. It is not organized into columns that represent sensory input from each tooth or direction of stimulation. These results demonstrate that intrinsic signal optical imaging is a valid tool for investigating neural responses and neuroplasticity in the somatosensory cortex that represents teeth.