METHYLATION MAP OF XENOPUS-LAEVIS RIBOSOMAL-RNA

METHYLATION MAP OF XENOPUS-LAEVIS RIBOSOMAL-RNA
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DOI:
10.1038/288293a0
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发表时间:
1980-01-01
期刊:
影响因子:
64.8
通讯作者:
MADEN, BEH
MADEN, BEH
中科院分区:
综合性期刊1区
文献类型:
--
作者:
MADEN, BEH

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X. laevis rRNA 中的甲基化核苷酸分布广泛但不均匀。在18S rRNA中,2''-O-甲基化部分集中在5''区域,碱基甲基化部分集中在3''末端附近。在 28S rRNA 中,甲基在 5'' 区域中不常见,在中心区域中较为常见,在 3'' 末端附近的 1100 个核苷酸区域中丰富。
The methylated nucleotides in X. laevis rRNA are broadly but non-uniformly distributed. In 18S rRNA, 2''-O-methylations are partly concentrated in the 5'' region and base methylations near the 3'' end. In 28S rRNA, methyl groups are infrequent in the 5'' region, moderately frequent in the central region and abundant in a 1100-nucleotide tract near the 3'' end.