INDUCTION OF NEURONAL BRANCHING IN CAENORHABDITIS-ELEGANS
INDUCTION OF NEURONAL BRANCHING IN CAENORHABDITIS-ELEGANS
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DOI：
10.1126/science.6857263
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发表时间：
1983-01-01
期刊：
影响因子：
56.9
通讯作者：
SULSTON, JE
中科院分区：
文献类型：
--
作者：
CHALFIE, M;THOMSON, JN;SULSTON, JE
秀丽隐杆线虫的2个胚胎后触觉受体神经元产生于基本相同的细胞系，具有相同的超微结构特征。这些细胞分布在动物体内的不同位置，它们的神经元分支、连通性和功能也各不相同。当细胞被突变或激光损伤置于相似位置时，这些结构和功能上的差异是看不到的。这些细胞的一些（但可能不是全部）分化特性是它们细胞环境的结果。
The 2 postembryonic touch receptor neurons in the nematode C. elegans arise from essentially identical cell lineages and have the same ultrastructural features. The cells are found in different positions in the animal and differ in neuronal branching, connectivity and function. These structural and functional differences are not seen when cells are placed in similar positions by mutation or laser-induced damage. Some, but probably not all, of the differentiated properties of these cells are a consequence of their cellular environment.