Ylide formal [4 + 1] annulation.
Ylide formal [4 + 1] annulation.
复制标题
DOI：
10.1039/c4ob02556c
复制
发表时间：
2015-02
影响因子：
3.2
通讯作者：
Chunyin Zhu;Ya Ding;L. Ye
中科院分区：
文献类型：
--
作者：
Chunyin Zhu;Ya Ding;L. Ye
在过去的几十年里，叶立德化学已经显著地扩展到烯化和小环形成之外的领域，其中叶立德[4+1]环化得到了广泛的探索，通过这种转化可以很容易地构建五元环结构，如二氢呋喃、异恶唑、吡咯烷、吲哚、二氢吡唑和环戊酮。本文对这一领域的最新进展进行了综述。回顾了Ylide[4+1]环，强调了它们的产品多样性、选择性和适用性，并在可能的情况下介绍了其机理基础。
Over the past few decades, ylide chemistry has been significantly extended to an area beyond olefination and small ring formation, among which ylide [4 + 1] annulation has been extensively explored, and five-membered ring structures, such as dihydrofurans, isoxazolines, pyrrolines, indoles, dihydropyrazoles and cyclopentenones, can be readily constructed through this type of transformation. An overview of the recent advances in this field is presented herein. Ylide [4 + 1] annulations are reviewed by highlighting their product diversity, selectivity and applicability, and the mechanistic rationale is presented when possible.