Erythrocytosis and hyperlipemia as manifestations of hepatic carcinoma.
Erythrocytosis and hyperlipemia as manifestations of hepatic carcinoma.
复制标题
红细胞增多和高脂血症是肝癌的表现。
作者：
M. Santer;T. Waldmann;H. Fallon
代谢和血液学异常被描述为原发性肝肿瘤的表现。红细胞增多症是这些继发表现中最常见的，在一系列研究中，有 11.7% 的患者出现红细胞增多症。 1 不太常见的是高胆固醇血症、2,3 骨质疏松症、2,4 卟啉症、5 性早熟、6 和低血糖 7 已有报道。本报告描述了一名患有肝细胞癌的年轻成人中红细胞增多和高脂血症的发生情况。进行了研究以阐明这些异常的机制。了解与肝癌相关的异常代谢变化可能有助于诊断不明原因的肝脏疾病。方法 临床化学实验室按照标准方法进行常规实验室操作，包括测定肝功能和胆固醇水平8。使用碘化 I 131 血清白蛋白（人）通过同位素稀释技术测定血浆体积。根据血细胞比容和测定的血浆体积计算红细胞体积。提取血清和生理盐水
METABOLIC and hematologic abnormalities have been described as manifestations of primary hepatic neoplasms. Erythrocytosis is the most common of these secondary manifestations, occurring in 11.7% of patients in one series. 1 Less commonly, hypercholesterolemia, 2,3 osteoporosis, 2,4 porphyria, 5 precocious puberty, 6 and hypoglycemia 7 have been reported. This report describes the occurrence of erythrocytosis and hyperlipemia in a young adult with hepatic cell carcinoma. Studies were done to clarify the mechanisms of these abnormalities. Awareness of the unusual metabolic alterations associated with hepatoma may assist in the diagnosis of obscure hepatic disease. Methods Routine laboratory procedures including determinations of liver function and cholesterol levels 8 were performed by the clinical chemistry laboratory by standard methods. Plasma volume was determined by the isotope dilution technique using iodinated I 131 serum albumin (human). Red blood cell volume was calculated from the hematocrit and the determined plasma volume. Serum and saline extracted