Non-adherence to anti-tuberculosis treatment, reasons and associated factors among TB patients attending at Gondar town health centers, Northwest Ethiopia.
Non-adherence to anti-tuberculosis treatment, reasons and associated factors among TB patients attending at Gondar town health centers, Northwest Ethiopia.
复制标题
DOI：
10.1186/s13104-018-3789-4
复制
发表时间：
2018-10-01
影响因子：
1.8
通讯作者：
Azagew AW
中科院分区：
文献类型：
--
作者：
Mekonnen HS;Azagew AW
本研究的目的是评估在Gondar镇卫生中心就诊的结核病患者中不坚持抗结核治疗的患病率、原因和相关因素。共纳入314名参与者，应答率为97.5%。参与者平均年龄为35.94 （SD±13.83）岁。抗结核治疗的总不依从率为21.2% （95% CI 17.2, 26.1）。继续治疗阶段（AOR = 2.27, 95% CI(1.54, 5.94)）、合并一种以上疾病（AOR = 6.22, 95% CI(2.21, 17.48)）、对结核病和抗结核治疗的认识不足（AOR = 4.11, 95% CI 1.57, 10.75）、不良的医患关系（AOR = 4.60, 95% CI 1.63, 12.97）和酒精摄入（AOR = 5.03, 95% CI 1.54, 16.40）与不依从性显著相关。遗忘40例（23.1%）、忙于其他工作35例（20.2%）和外出24例（13.9%）是参与者中断服用抗结核药物的主要原因。本文的在线版本（10.1186/s13104-018-3789-4）包含补充材料，授权用户可使用。
The aim of this study was to assess the prevalence of non-adherence to anti-tuberculosis treatment, reasons and associated factors among TB patients attending at Gondar town health centers. A total of 314 participants were included with the response rate of 97.5%. The mean age of participants was 35.94 (SD ± 13.83) years. The overall rate of non-adherence to anti-TB treatment was 21.2% (95% CI 17.2, 26.1). Continuation phase of treatment (AOR = 2.27, 95% CI (1.54, 5.94)), presence of more than one co-morbidity (AOR = 6.22; 95% CI (2.21, 17.48)), poor knowledge about TB and anti-TB therapy (AOR = 4.11; 95% CI 1.57, 10.75), poor patient-provider relationship (AOR = 4.60, 95% CI 1.63, 12.97), and alcohol intake (AOR = 5.03; 95% CI 1.54, 16.40) were significantly associated with non-adherence. Forgetting 40 (23.1%), Being busy with other work 35 (20.2%), and being out of home/town 24 (13.9%) were the major reasons of participants for interruption of taking anti-TB medications. The online version of this article (10.1186/s13104-018-3789-4) contains supplementary material, which is available to authorized users.