A randomized, prospective study of the effects of Tai Chi Chun exercise on bone mineral density in postmenopausal women
A randomized, prospective study of the effects of Tai Chi Chun exercise on bone mineral density in postmenopausal women
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DOI：
10.1016/j.apmr.2003.08.091
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发表时间：
2004-05-01
影响因子：
4.3
通讯作者：
Lee, SH
中科院分区：
文献类型：
--
作者：
Chan, KM;Qin, L;Lee, SH
目的：为了评估程序太极拳（TCC）运动对早期绝经后妇女承重骨的潜在益处，设计：配对和随机前瞻性干预。设置：大学医学院。参与者：132名健康绝经后妇女（平均年龄，54.+/-研究对象为绝经10年以内的女性（年龄3.5岁），随机分为TCC运动组（n=67）和久坐对照组（n=65）。干预：TCC组在监督下进行TCC运动，每天45分钟，每周5天，持续12个月;对照组保持久坐的生活方式。采用双能X线吸收法测量腰椎和股骨近端的骨密度（BMD），采用多层外周定量计算机断层扫描（pQCT）测量胫骨远端的骨密度。两组患者在12个月后重复所有BMD测量。骨折率也记录。结果：基线测量显示TCC和对照组之间的年龄，人体测量变量和月经状态的同质性。TCC组和对照组分别有81.6%和83.1%的受试者完成了12个月的随访研究。骨密度测量结果显示，TCC和久坐对照组受试者在所有测量的骨骼部位都有普遍的骨丢失，但据报道TCC组的骨丢失率较低。骨丢失显著延迟2.6- 3.6倍（P
Objective: To evaluate the potential benefits of programmed Tai Chi Chun (TCC) exercise on the weight-bearing bones of early postmenopausal women.Design: Age-matched and randomized prospective intervention.Setting: University medical school.Participants: One hundred thirty-two healthy postmenopausal women (mean age, 54.+/-3.5y) within 10 years of menopause onset were recruited and randomized into the TCC exercise group (n=67) or the sedentary control group (n=65).Intervention: Supervised TCC exercise was performed by the TCC group for 45 minutes a day, 5 days a week, for 12 months; control subjects retained a sedentary life style.Main Outcome Measures: Bone mineral density (BMD) was measured in the lumbar spine and proximal femur by using dual-energy x-ray absorptiometry and in the distal tibia by using multislice peripheral quantitative computed tomography (pQCT). All BMD measurements were repeated after 12 months in both groups. Fracture rate was also documented.Results: Baseline measurements showed homogeneity in age, anthropometric variables, and menstruation status between the TCC and control groups. Exactly 81.6% of the subjects in the TCC group and 83.1% of subjects in the control group completed the 12-month follow-up study. BMD measurements revealed a general bone loss in both TCC and sedentary control subjects at all measured skeletal sites, but with a reportedly slower rate in the TCC group. A significant 2.6- to 3.6-fold retardation of bone loss (P