Absence of ocular effects after either single or repeated exposure to 10 mW/cm(2) from a 60 GHz CW source.

Absence of ocular effects after either single or repeated exposure to 10 mW/cm(2) from a 60 GHz CW source.
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单次或重复暴露于 60 GHz 连续波光源 10 mW/cm(2) 下后,不会对眼睛产生影响。

DOI:
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发表时间:
1999
影响因子:
1.9
通讯作者:
J. Monahan
J. Monahan
中科院分区:
生物学4区
文献类型:
--
作者:
H. Kues;S. D'Anna;R. Osiander;W. Green;J. Monahan

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本研究旨在检查与暴露于毫米波(60 GHz)相关的眼部效应。兔子作为主要实验对象。为了证实兔子实验在高等物种中的结果,研究的第二阶段使用了非人类灵长类动物(猕猴)。首先,本研究使用时间分辨红外辐射测量来评估在60 GHz下工作的不同天线产生的场分布模式。这些结果使我们能够选择产生均匀能量分布的天线以及暴露实验对象的最佳距离。然后,该研究检查了在10 mW/cm(2)的入射功率密度下暴露后的眼部变化。家兔和非人灵长类动物的急性暴露包括单次8 h暴露,重复暴露方案包括连续5天的5次单独4 h暴露。每只动物的一只眼睛暴露,对侧眼睛作为假暴露对照。在执行后诊断检查后,对动物实施安乐死并摘除眼睛。通过光学显微镜和透射电子显微镜检查眼组织。对急性和反复暴露的兔子的眼睛进行的显微镜检查和诊断程序都没有发现任何可归因于10 mW/cm毫米波暴露的眼部变化(2)。在类似的暴露后对灵长类动物进行的检查也未能检测到暴露引起的任何眼部变化。根据我们的研究结果,我们得出结论,单次或重复暴露于10 mW/cm(2)的60 GHz CW辐射不会导致任何可检测的眼部损伤。
This study was designed to examine ocular effects associated with exposure to millimeter waves (60 GHz). Rabbits served as the primary experimental subjects. To confirm the results of the rabbit experiments in a higher species, the second phase of the study used nonhuman primates (Macaca mulatta). First, this study used time-resolved infrared radiometry to assess the field distribution patterns produced by different antennas operating at 60 GHz. These results allowed us to select an antenna that produced a uniform energy distribution and the best distance at which to expose our experimental subjects. The study then examined ocular changes after exposure at an incident power density of 10 mW/cm(2). Acute exposure of both rabbits and nonhuman primates consisted of a single 8 h exposure, and the repeated exposure protocol consisted of five separate 4 h exposures on consecutive days. One eye in each animal was exposed and the contralateral eye served as the sham-exposed control. After postexposure diagnostic examinations, animals were euthanized and the eyes were removed. Ocular tissue was examined by both light and transmission electron microscopy. Neither microscopic examinations nor the diagnostic procedures performed on the eyes of acute and repeatedly exposed rabbits found any ocular changes that could be attributed to millimeter-wave exposure at 10 mW/cm(2). Examination of the primates after comparable exposures also failed to detect any ocular changes due to exposure. On the basis of our results, we conclude that single or repeated exposure to 60 GHz CW radiation at 10 mW/cm(2) does not result in any detectable ocular damage.