Potential protective effects of breast milk and amniotic fluid against novel coronavirus SARS-CoV-2 through decoy receptors.
Potential protective effects of breast milk and amniotic fluid against novel coronavirus SARS-CoV-2 through decoy receptors.
复制标题
母乳和羊水通过诱饵受体对新型冠状病毒 SARS-CoV-2 的潜在保护作用。
DOI：
10.1111/pai.13672
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发表时间：
2022
期刊：
影响因子：
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通讯作者：
Rees A
中科院分区：
文献类型：
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作者：
Rees A
1.在以前的冠状病毒介导的大流行期间，如严重急性呼吸综合征（SARS）和中东呼吸综合征（MERS），孕妇感染与胎儿和母亲死亡率高有关。然而，COVID-19在孕妇和非孕妇中的特征非常相似，虽然妊娠期间严重的COVID-19会增加早产和重症监护的风险，但大多数孕妇，无论是否有SARS-CoV-2感染的症状，在妊娠期间都不会出现严重的并发症。2同样，SARS-CoV-2垂直传播的病例很少，新生儿患严重疾病的风险也很低。3了解孕妇和新生儿对严重COVID-19的恢复机制对于确保护理中的持续警惕以及深入了解疾病发病机制和治疗机会至关重要。
1. OBJECTIVEInfection of pregnant women during previous coronavirus‐mediated pandemics, such as severe acute respiratory syndrome (SARS) and Middle East respiratory syndrome (MERS), was associated with high rates of fetal and maternal demise. However, the characteristics of COVID‐19 in pregnant and non‐pregnant women are very similar, and while severe COVID‐19 in pregnancy brings increased risk of preterm birth and intensive care admission, 1 most pregnant women, be they symptomatic or asymptomatic for SARS‐CoV‐2 infection, do not experience severe complications in pregnancy. 2 Similarly, cases of SARS‐CoV‐2 vertical transmission are rare and there is low risk of serious disease for the neonate. 3 Understanding the mechanisms of resilience against severe COVID‐19 in pregnant women and the newborn is critical to ensure ongoing vigilance in care and to provide insight into disease pathogenesis and therapeutic opportunities.