Theta synchronization networks emerge during human object-place memory encoding
Theta synchronization networks emerge during human object-place memory encoding
复制标题
DOI：
10.1097/wnr.0b013e3280586760
复制
发表时间：
2007-03-26
期刊：
影响因子：
1.7
通讯作者：
Yamaguchi, Yoko
中科院分区：
文献类型：
--
作者：
Sato, Naoyuki;Yamaguchi, Yoko
最近的啮齿动物海马体研究表明，θ节律依赖的神经动力学（'θ相位进动'）是必不可少的在线记忆的形成。一项计算研究表明，相位进动使人类的物体-位置关联记忆与自愿的眼球运动，虽然它仍然是一个悬而未决的问题，人类大脑是否使用的动力学。在这里，我们在根据之前的计算研究设计的物体-位置关联记忆中阐明了人类头皮脑电中随后的记忆相关活动。我们的研究结果成功地表明，随后的记忆回忆的特点是增加θ功率和连贯性，并进一步，多个θ同步网络出现。这些发现表明，人类的θ动力学与啮齿动物在情景记忆形成中是共同的。
Recent rodent hippocampus studies have suggested that theta rhythm-dependent neural dynamics ('theta phase precession') is essential for an on-line memory formation. A computational study indicated that the phase precession enables a human object-place association memory with voluntary eye movements, although it is still an open question whether the human brain uses the dynamics. Here we elucidated subsequent memory-correlated activities in human scalp electroencephalography in an object-place association memory designed according the former computational study. Our results successfully demonstrated that subsequent memory recall is characterized by an increase in theta power and coherence, and further, that multiple theta synchronization networks emerge. These findings suggest the human theta dynamics in common with rodents in episodic memory formation.