Near-infrared frequency domain system and fast inverse Monte Carlo algorithm for endoscopic measurement of tubular tissue.
Near-infrared frequency domain system and fast inverse Monte Carlo algorithm for endoscopic measurement of tubular tissue.
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DOI：
10.3233/xst-2010-0278
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发表时间：
2011
影响因子：
3
通讯作者：
Huijuan Zhao;Xiaoqing Zhou;Y. Fan;F. Gao
中科院分区：
文献类型：
--
作者：
Huijuan Zhao;Xiaoqing Zhou;Y. Fan;F. Gao
本文研制了一套用于内窥镜测量的近红外漫反射系统，并提出了一种提取管状组织光学特性的逆算法。测量系统工作在频域模式下，并采用定制探头进行宫颈癌的内窥镜检测。测量精度的实验表明，交流幅值和相位滞后的模型与数据的失配分别小于3.7%和6.7%。为了便于提取管状组织的光学特性，同时减小初始假设对重建精度的影响，提出了一种基于聚类分析的快速逆蒙特卡罗模拟算法。仿真结果表明，采用该逆算法恢复的吸收系数相对误差小于5.8%，散射系数相对误差小于10.2%。并对两个管状实体模型进行了内窥镜测量，以评价系统和倒置方案。结果表明，相对误差小于20%。
A near infrared diffuse reflectance system for endoscopic measurement and an inverse algorithm for extracting optical properties of tubular tissues were developed in this paper. The measurement system worked in the frequency domain mode and a custom probe was employed for endoscopic detection of cervical cancer. Experiments for evaluating the measurement accuracy indicate that the model-to-data mismatch for the AC amplitude and phase lag is less than 3.7% and 6.7%, respectively. To facilitate the extraction of the optical properties in tubular tissues and to minimize the influence of the initial guess on the reconstruction accuracy, a fast inverse Monte Carlo simulation algorithm with cluster analysis method was proposed. Simulation results showed that the relative errors of the absorption coefficient recovered using the proposed inverse algorithm are less than 5.8% and those of the sacttering coefficient are less than 10.2%. Endoscopic measurement on two tubular solid phantoms were also carried out to evaluate the system and the inversion scheme. The results demonstrated that less than 20% relative error can be achieved.