Diagnostic accuracy of colour Doppler ultrasonography, CT angiography and blood-pool-enhanced MR angiography in assessing carotid stenosis: a comparative study with DSA in 170 patients

Diagnostic accuracy of colour Doppler ultrasonography, CT angiography and blood-pool-enhanced MR angiography in assessing carotid stenosis: a comparative study with DSA in 170 patients
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DOI:
10.1007/s11547-011-0651-3
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发表时间:
2012-02-01
期刊:
影响因子:
8.9
通讯作者:
Passariello, R.
Passariello, R.
中科院分区:
医学2区
文献类型:
--
作者:
Anzidei, M.;Napoli, A.;Passariello, R.

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目的.本研究采用数字减影血管造影(DSA)作为参考标准,前瞻性评价彩色多普勒超声(CDUS)、首过(FP)和稳态(SS)对比增强磁共振血管造影(MRA)和计算机断层扫描血管造影(CTA)对颈动脉的诊断性能。对170例有脑血管事件史且怀疑颈动脉狭窄的患者进行了CDUS、血池MRA、CTA和DSA检查。计算CDUS、FP MRA、SS MRA和CTA的准确性、敏感性、特异性、阳性预测值(PPV)和阴性预测值(NPV)。采用McNemar和Wilcoxon检验和受试者工作特征(ROC)曲线分析确定显著性差异(p
Purpose. This study was undertaken to prospectively evaluate the diagnostic performance of colour Doppler ultrasonography (CDUS), first-pass (FP) and steady-state (SS) contrast-enhanced magnetic resonance angiography (MRA) and computed tomography angiography (CTA) of the carotid arteries using digital subtraction angiography (DSA) as the reference standard.Materials and methods. A total of 170 patients with previous cerebrovascular events and suspected carotid artery stenoses underwent CDUS, blood-pool MRA, CTA and DSA. Accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated for CDUS, FP MRA, SS MRA and CTA. The McNemar and Wilcoxon tests and receiver operating characteristic (ROC) curve analysis were used to determine significant differences (p