Apraxia of lid opening due to a small lesion in basal ganglia: two case reports
Apraxia of lid opening due to a small lesion in basal ganglia: two case reports
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DOI：
10.1136/jnnp.2009.184846
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发表时间：
2010-06
期刊：
影响因子：
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通讯作者：
M. Hirose;H. Mochizuki;M. Honma;Toru Kobayashi;M. Nishizawa;Y. Ugawa
中科院分区：
文献类型：
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作者：
M. Hirose;H. Mochizuki;M. Honma;Toru Kobayashi;M. Nishizawa;Y. Ugawa
开眼睑失用症(ALO)是睁眼失用症的同义词，是一种以无法随意睁开眼睛为特征的残疾综合征，患者有时试图通过收缩额肌和用自己的手指触摸眼皮来睁开眼睛(感官技巧)。这种症状通常与眼睑痉挛和/或上睑下垂有关，有时出现在帕金森氏症或其他运动障碍的患者中。这些报道表明，ALO可能是由基底节的一些损害引起的。为了确定导致某些症状的特定部位，具有目标症状的患者通常可以为我们提供有用的信息。然而，ALO很少是由单个脑血管病变引起的。1少数ALO患者在大脑中动脉区域的非优势侧有大的缺血性病变。1一例报告描述了引起ALO的壳核的小病变。2在这里，我们报告了两例由于基底节的小病变而导致的ALO患者，并讨论了ALO的机制。2008年12月10日，患者1出现右侧偏瘫，睁眼困难。脑部CT显示…
The apraxia of lid opening (ALO), a synonym for apraxia of eye opening, is a disabling syndrome characterised by an inability to open the eyes at will, and patients sometimes try to open their eyes by contracting the frontalis muscles and touching their eye lids with their own fingers (sensory trick). This symptom is often associated with blepharospasm and/or ptosis and sometimes seen in patients with Parkinson's disease or other movement disorders. These reports suggest that ALO may be produced by some lesions at the basal ganglia. To determine specific sites responsible for some symptoms, patients with the target symptoms resulting from a small cerebrovascular lesion usually can provide us with useful information. However, the ALO is rarely produced by a single cerebrovascular lesion.1 A few patients with ALO had a large ischaemic lesion at the non-dominant side in the middle cerebral artery territory.1 One case report described a small lesion at the putamen causing ALO.2 Here, we present two patients with ALO due to a small lesion in the basal ganglia and discuss mechanisms for ALO. On 10 December 2008, patient 1 developed right hemiparesis and had difficulty in opening her eyes. A brain CT showed …