Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2'-deoxy and 2',3'-dideoxynucleosides.
Continuous flow photocatalysis enhanced using an aluminum mirror: rapid and selective synthesis of 2'-deoxy and 2',3'-dideoxynucleosides.
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DOI：
10.1039/c2cc33356b
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发表时间：
2012-06
影响因子：
4.9
通讯作者：
Bo Shen;Matthew W. Bedore;A. Sniady;T. Jamison
中科院分区：
文献类型：
--
作者：
Bo Shen;Matthew W. Bedore;A. Sniady;T. Jamison
开发了一种独特的光化学流动反应器，该反应器具有石英管、铝镜和温度控制，用于光诱导电子转移脱氧反应，以产生2 '-脱氧和2'，3 '-双脱氧核苷。连续流动形式显著提高了反应的效率和选择性。
A unique photochemical flow reactor featuring quartz tubing, an aluminum mirror and temperature control has been developed for the photo-induced electron-transfer deoxygenation reaction to produce 2'-deoxy and 2',3'-dideoxynucleosides. The continuous flow format significantly increased the efficiency and selectivity of the reaction.