Regulation of nuclear morphology by actomyosin components and cell geometry

Regulation of nuclear morphology by actomyosin components and cell geometry
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肌动球蛋白成分和细胞几何形状对核形态的调节

DOI:
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发表时间:
2015
期刊:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society
影响因子:
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通讯作者:
G. Shivashankar
G. Shivashankar
中科院分区:
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文献类型:
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作者:
Nisha M. Ramdas;Qingsen Li;G. Shivashankar

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细胞外微环境信号调节细胞骨架与核连接之间的耦合,以调节基因表达谱。然而,肌动球蛋白组装对细胞核形态的影响尚不清楚。在本文中,我们定量证明了细胞几何形状和特定肌动球蛋白分子成分在控制核形态中的作用。
Extracellular microenvironmental signals modulate the coupling between cytoskeleton to nuclear links to regulate gene expression profiles. However the influence of actomyosin assembly on the morphology of the nucleus is not well understood. In this paper, we quantitatively demonstrate the role of cell geometry and specific actomyosin molecular components in their control of nuclear morphology.
DOI: 10.1073/pnas.94.3.849
发表时间: 1997-02-04
影响因子: 11.1
作者:
Maniotis, AJ;Chen, CS;Ingber, DE
通讯作者: Ingber, DE
DOI: 10.1016/j.tcb.2013.11.004
发表时间: 2014-04
影响因子: 19
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