Cancer screening simulation models: a state of the art review.
Cancer screening simulation models: a state of the art review.
复制标题
DOI：
10.1186/s12911-021-01713-5
复制
发表时间：
2021-12-20
影响因子：
3.5
通讯作者：
Nevalainen J
中科院分区：
文献类型：
--
作者：
Bespalov A;Barchuk A;Auvinen A;Nevalainen J
如今，在文献中可以找到用于癌症筛查评估和决策的各种模拟方法。本文概述了用于评估乳腺癌、肺癌、结直肠癌、前列腺癌和宫颈癌筛查项目的方法。我们的主要目标是描述不同癌症部位和研究人群的方法学方法和趋势，并评估癌症筛查模拟研究的质量。在 Medline、Web of Science 和 Scopus 数据库中进行了系统的文献检索。检索时间范围仅限于 1999 年至 2018 年，共找到 7101 项研究。其中，符合纳入标准的研究有 621 篇，检索全文 587 篇，选择其中 300 篇进行分析。最终，分析中使用了 263 篇全文（分析期间排除了 37 篇）。使用为本研究创建的清单进行模型的描述性和趋势分析。目前，癌症筛查建模中最常见的方法是个体水平马尔可夫模型（占出版物的 34%）和队列水平马尔可夫模型（41%）。最常评估的癌症类型是乳腺癌（25%）和结直肠癌（24%）。宫颈癌研究评估了筛查和疫苗接种（18%）或仅评估（13%）。大多数研究是针对北美 (42%) 和欧洲 (39%) 人群进行的。随着时间的推移，具有高质量分数的研究数量不断增加。我们的研究结果表明，癌症筛查建模的未来方向包括以筛查试验数据为补充的个体水平马尔可夫模型，以及在模型验证和数据开放方面的进一步努力。在线版本包含可在 10.1186/s12911-021-01713-5 获取的补充材料。
Nowadays, various simulation approaches for evaluation and decision making in cancer screening can be found in the literature. This paper presents an overview of approaches used to assess screening programs for breast, lung, colorectal, prostate, and cervical cancers. Our main objectives are to describe methodological approaches and trends for different cancer sites and study populations, and to evaluate quality of cancer screening simulation studies. A systematic literature search was performed in Medline, Web of Science, and Scopus databases. The search time frame was limited to 1999–2018 and 7101 studies were found. Of them, 621 studies met inclusion criteria, and 587 full-texts were retrieved, with 300 of the studies chosen for analysis. Finally, 263 full texts were used in the analysis (37 were excluded during the analysis). A descriptive and trend analysis of models was performed using a checklist created for the study. Currently, the most common methodological approaches in modeling cancer screening were individual-level Markov models (34% of the publications) and cohort-level Markov models (41%). The most commonly evaluated cancer types were breast (25%) and colorectal (24%) cancer. Studies on cervical cancer evaluated screening and vaccination (18%) or screening only (13%). Most studies have been conducted for North American (42%) and European (39%) populations. The number of studies with high quality scores increased over time. Our findings suggest that future directions for cancer screening modelling include individual-level Markov models complemented by screening trial data, and further effort in model validation and data openness. The online version contains supplementary material available at 10.1186/s12911-021-01713-5.
登录
查看更多内容
影响因子：
6.6
作者：
Etzioni, R;Cha, R;Cowen, ME
通讯作者：
Cowen, ME
影响因子：
6.2
作者：
Joseph DA;Meester RG;Zauber AG;Manninen DL;Winges L;Dong FB;Peaker B;van Ballegooijen M
通讯作者：
van Ballegooijen M
影响因子：
5.5
作者：
Selby K;Bartlett-Esquilant G;Cornuz J
通讯作者：
Cornuz J
影响因子：
4
作者：
Campos NG;Tsu V;Jeronimo J;Mvundura M;Kim JJ
通讯作者：
Kim JJ
影响因子：
50.5
作者：
Lee, SJ;Zelen, M
通讯作者：
Zelen, M