Immobilized monolithic enzyme reactors for application in proteomics and pharmaceutics
Immobilized monolithic enzyme reactors for application in proteomics and pharmaceutics
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DOI：
10.1007/s00216-009-2998-z
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发表时间：
2009-08
影响因子：
4.3
通讯作者：
J. Sproß;A. Sinz
中科院分区：
文献类型：
--
作者：
J. Sproß;A. Sinz
在过去的几年中，在各种各样的应用程序中使用单片支撑已经迅速扩展。本文给出的应用实例表明，由整体介质制备的生物反应器和亲和介质的色谱性能优于传统的基于颗粒的系统。易于制造和修改结合长寿命的整体柱和他们的潜力，在全自动分析系统中使用，使他们有吸引力的工具越来越多的应用。
The use of monolithic supports for a wide variety of applications has rapidly expanded during the past few years. The examples for applications of monoliths presented herein show that the chromatographic performance of bioreactors and affinity media prepared from monolithic media is superior to that of conventional particle-based systems. The ease of fabrication and modification combined with the long lifetime of the monolithic columns and their potential to be used in fully automated analytical systems make them attractive tools for an increasing number of applications.