Curcuma zedoaria 50% methanol extracts increase adiponectin secretion by enhancing PPARγ mRNA expression in 3T3-L1 cells.

Curcuma zedoaria 50% methanol extracts increase adiponectin secretion by enhancing PPARγ mRNA expression in 3T3-L1 cells.
复制标题

莪术 50% 甲醇提取物通过增强 3T3-L1 细胞中 PPARγ mRNA 的表达来增加脂联素分泌。

DOI:
10.1093/bbb/zbac098
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发表时间:
2022
期刊:
Bioscience, Biotechnology, and Biochemistry
影响因子:
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通讯作者:
Keizo Hosokawa
Keizo Hosokawa
中科院分区:
--
文献类型:
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作者:
Kazuaki Yamasaki;Isoko Kuriyama;Reiko Nakai;Keizo Hosokawa

文献摘要

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莪术是其属的特征物种,几乎不含姜黄素。在这里,我们证明了C。50%莪术醇提物通过增强3 T3-L1细胞中PPAR γmRNA的表达而增加脂联素的分泌。这些结果表明C.莪术油可用于预防/改善生活方式相关疾病,例如糖尿病和动脉粥样硬化。
Curcuma zedoariais a characteristic species of its genus that contains little to no curcuminoid. Here, we demonstrate thatC. zedoariaextracts with 50% methanol increases adiponectin secretion into the media by enhancingPPARγmRNA expression in 3T3-L1 cells. These results indicate thatC. zedoariamay be useful for preventing/improving lifestyle-related diseases such as diabetes and atherosclerosis.