The Role of Brown Adipose Tissue Dysfunction in the Development of Cardiovascular Disease.
The Role of Brown Adipose Tissue Dysfunction in the Development of Cardiovascular Disease.
复制标题
棕色脂肪组织功能障碍在心血管疾病发展中的作用
DOI:
10.3389/fendo.2021.652246
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发表时间:
2021
影响因子:
5.2
通讯作者:
Ruan CC
中科院分区:
文献类型:
--
作者:
Chen HJ;Meng T;Gao PJ;Ruan CC
Brown adipose tissue (BAT), consisted of brown adipocytes and stromal vascular fraction, which includes endothelial cells, lymphocytes, fibroblasts and stem cells, plays a vital role in regulating cardiovascular health and diseases. As a thermogenic organ, BAT can influence body through strengthening energy expenditure by promoting glucose and lipid metabolism. In addition, BAT is also an endocrine organ which is able to secret adipokines in an autocrine and/or paracrine fashion. BAT plays a protective role in cardiovascular system through attenuating cardiac remodeling and suppressing inflammatory response. In this review, we summarize the advances from the discovery of BAT to the present and provide an overview on the role of BAT dysfunction in cardiovascular diseases.
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影响因子:
4.6
作者:
Dowal L;Parameswaran P;Phat S;Akella S;Majumdar ID;Ranjan J;Shah C;Mogre S;Guntur K;Thapa K;Gesta S;Vishnudas VK;Narain NR;Sarangarajan R
通讯作者:
Sarangarajan R
影响因子:
16.6
作者:
Berbée JF;Boon MR;Khedoe PP;Bartelt A;Schlein C;Worthmann A;Kooijman S;Hoeke G;Mol IM;John C;Jung C;Vazirpanah N;Brouwers LP;Gordts PL;Esko JD;Hiemstra PS;Havekes LM;Scheja L;Heeren J;Rensen PC
通讯作者:
Rensen PC
DOI:
10.1152/ajpendo.00009.2005
发表时间:
2005-10-01
影响因子:
5.1
作者:
Granneman, JG;Li, PP;Lu, YY
通讯作者:
Lu, YY
影响因子:
37.8
作者:
Chang L;Villacorta L;Li R;Hamblin M;Xu W;Dou C;Zhang J;Wu J;Zeng R;Chen YE
通讯作者:
Chen YE
影响因子:
64.5
作者:
Bersell, Kevin;Arab, Shima;Kuehn, Bernhard
通讯作者:
Kuehn, Bernhard