Drug-provoked psoriasis: is it drug induced or drug aggravated?: understanding pathophysiology and clinical relevance.

Drug-provoked psoriasis: is it drug induced or drug aggravated?: understanding pathophysiology and clinical relevance.
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药物诱发的牛皮癣:是药物诱发的还是药物加重的?:了解病理生理学和临床相关性。

DOI:
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发表时间:
2010
期刊:
˜The œJournal of clinical and aesthetic dermatology
影响因子:
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通讯作者:
J. D. Del Rosso
J. D. Del Rosso
中科院分区:
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文献类型:
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作者:
Grace K. Kim;J. D. Del Rosso

文献摘要

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Psoriasis is a commonly encountered dermatosis with a variety of internal and external paradoxical factors contributing to the clinical course of the disease. There are several drugs described in the literature that have been associated with the initiation, exacerbation, and aggravation of psoriasis. Understanding the pathophysiology can provide clues to treatment and management of drug-induced and drug-aggravated psoriasis, which may be indistinguishable from idiopathic psoriasis. The clinical manifestations of drug-associated psoriasis can range from plaque-type psoriasis to severe erythroderma, thus warranting astute and sustained clinical observation.