AN EVALUATION OF THE INTEGRITY OF THE BLOOD-TESTIS BARRIER BY MAGNETIC-RESONANCE-IMAGING
AN EVALUATION OF THE INTEGRITY OF THE BLOOD-TESTIS BARRIER BY MAGNETIC-RESONANCE-IMAGING
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DOI：
10.1002/mrm.1910220109
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发表时间：
1991-11-01
影响因子：
3.3
通讯作者：
VANTHIEL, DH
中科院分区：
文献类型：
--
作者：
FARGHALI, H;WILLIAMS, DS;VANTHIEL, DH
本研究旨在非侵入性评价静脉注射钆喷酸葡胺（Gd-PTDM）增强磁共振成像（MRI）在评估血睾屏障（BTB）完整性方面的有效性。在接受细胞松弛素D或酒精治疗的大鼠中，在Gd-PTDM前和后图像中测量不同图像切片的强度。结果发现，MRI可用于评估BTB的完整性，并可能是一个有用的工具，在评估潜在的毒性剂，影响睾丸，特别是那些影响BTB。出版社：Academic Press，Inc.
This present investigation was initiated to noninvasively evaluate the usefulness of intravenous gadopentetate dimeglumine (Gd‐PTDM) ‐enhanced magnetic resonance imaging (MRI) in assessing the integrity of the blood‐testis barrier (BTB). The intensity of different image slices was measured in pre‐and post‐Gd‐PTDM images in rats receiving cytochalasin D or alcohol treatment. It was found that MRI can be used to assess the integrity of the BTB and may be a useful tool in the evaluation of potentially toxic agents that affect the testis, particularly those that affect the BTB. © 1991 Academic Press, Inc.