Blood supply management in times of SARS-CoV-2 pandemic - challenges, strategies adopted, and the lessons learned from the experience of a hospital-based blood centre
Blood supply management in times of SARS-CoV-2 pandemic - challenges, strategies adopted, and the lessons learned from the experience of a hospital-based blood centre
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DOI：
10.1111/vox.13019
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发表时间：
2020-10-26
期刊：
影响因子：
2.7
通讯作者：
Kumar, Karan
中科院分区：
文献类型：
--
作者：
Pandey, Hem Chandra;Coshic, Poonam;Kumar, Karan
在SARS-CoV-2大流行爆发后，人们对血液库存的维持提出了许多关注。这些关切是基于血液中心在以往大流行中报告血液成分短缺的经验。本研究试图了解SARS-CoV-2大流行对血液采集和需求的影响，以及灾难规划在维持充足库存方面的影响。方法使用血库管理软件回顾性收集COVID-19前和COVID-19时间段的血液供应和需求相关数据，并进行比较。结果与2019冠状病毒病爆发前相比，由于血液采集量（之前采集量的1/6至1/9）和需求量（之前需求量的1/2）不成比例地减少，红细胞库存量急剧下降。随着计划中的献血活动的取消，缓冲库存在三周内逐渐减少。相当于两周库存的缓冲库存使最初的封锁期间有足够的库存。随着血液采集量的减少，血小板库存也出现了类似的下降，但血小板需求量几乎成比例地减少，导致库存充足。在此期间，没有观察到红细胞和血小板的浪费增加。讨论血液和血液成分的缓冲储备，严格遵守输血触发，与临床工作人员的良好协调以及对输血请求进行前瞻性审查以确保合理输血是帮助我们在COVID初期成功维持输血要求的一些步骤-19大流行病。使用先进先出政策防止了因血液过期而造成的任何浪费。
Introduction Numerous concerns regarding maintenance of blood inventory have been raised after SARS-CoV-2 pandemic outbreak. These concerns were based on the experience of blood centres in previous pandemics where shortage of blood components was reported. The present study had tried to understand the impact of SARS-CoV-2 pandemic on blood collection and demand as well as the impact of disaster planning in maintaining an adequate inventory.Methods Data related to blood supply and demand were collected retrospectively using blood bank management software for pre-COVID-19 and COVID-19 time period and compared. Strategies adopted and effects of changes in existing disaster plans to maintain an adequate inventory were studied.Results A drastic fall in the red cell inventory was observed as compared to pre-COVID-19 time period was observed due to disproportionate decrease in blood collection (1/6 to 1/9 of the previous collection) and demand (1/2 of the previous demand). The buffer stock fell gradually over a period of three weeks with cancellation of planned blood donation drives. A buffer stock equivalent to 2-week inventory led to adequate inventory in the initial lockdown periods. Similar fall was observed in the platelet inventory with reduction in the blood collection but almost a proportionate reduction in the platelet demand led to adequate inventory. No increase in wastage was observed for both red cells and platelets during this period.Discussion A buffer stock of blood and blood components, strict adherence to the transfusion triggers, good coordination with the clinical staff and a prospective review of blood transfusion requests to ensure rational blood transfusion were some of the steps which helped us to successfully maintain transfusion requirements in the initial phases of the COVID-19 pandemic. Use of first-in-first-out policy prevented any wastage due to outdating of blood.