Brain dynamics in the comprehension of action-related language. A time-frequency analysis of mu rhythms
Brain dynamics in the comprehension of action-related language. A time-frequency analysis of mu rhythms
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DOI：
10.1016/j.neuroimage.2015.01.018
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发表时间：
2015-04-01
期刊：
影响因子：
5.7
通讯作者：
Magyari, Lilla
中科院分区：
文献类型：
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作者：
Moreno, Ivan;de Vega, Manuel;Magyari, Lilla
在额中央电极处记录的EEG μ节律（8-13 Hz）通常被认为是人类运动皮层活动的标记，因为当参与者执行动作时，当他们观察另一个动作时，甚至当他们想象执行动作时，它们被调制。在这项研究中，我们分析了mu节律的时频（TF）调制，而参与者阅读动作语言（“你会切草莓蛋糕”），抽象语言（“你会怀疑病人的论点”）和感知语言（“你会注意到明亮的一天”）。结果表明，在额中央部位的mu抑制与动作语言，而不是抽象或感知的语言。此外，条件之间的最大差异发生在句子的后期，当阅读第一个名词时（对比Action与Abstract），或者在动作动词之后的第二个名词时（对比Action与Perceptive）。这表明，运动激活与句子中单词的整合有关，而不仅仅是动作动词的词汇处理。源重构定位与动作句相关的mu抑制在前运动皮层（BA 6）。本研究表明：（1）对动作语言的理解激活了人脑中的运动网络;（2）这种激活是基于句子中多个单词的语义整合而在线发生的。(C)2015爱思唯尔公司All rights reserved.
EEG mu rhythms (8-13 Hz) recorded at fronto-central electrodes are generally considered as markers of motor cortical activity in humans, because they are modulated when participants perform an action, when they observe another's action or even when they imagine performing an action. In this study, we analyzed the time-frequency (TF) modulation of mu rhythms while participants read action language ("You will cut the strawberry cake"), abstract language ("You will doubt the patient's argument"), and perceptive language ("You will notice the bright day"). The results indicated that mu suppression at fronto-central sites is associated with action language rather than with abstract or perceptive language. Also, the largest difference between conditions occurred quite late in the sentence, while reading the first noun, (contrast Action vs. Abstract), or the second noun following the action verb (contrast Action vs. Perceptive). This suggests that motor activation is associated with the integration of words across the sentence beyond the lexical processing of the action verb. Source reconstruction localized mu suppression associated with action sentences in premotor cortex (BA 6). The present study suggests (1) that the understanding of action language activates motor networks in the human brain, and (2) that this activation occurs online based on semantic integration across multiple words in the sentence. (C) 2015 Elsevier Inc. All rights reserved.