Circadian phase-shifting effects of nocturnal exercise in older compared with young adults
Circadian phase-shifting effects of nocturnal exercise in older compared with young adults
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DOI：
10.1152/ajpregu.00761.2002
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发表时间：
2003-06-01
影响因子：
2.8
通讯作者：
Zee, PC
中科院分区：
文献类型：
--
作者：
Baehr, EK;Eastman, CI;Zee, PC
如果在一天中的正确时间进行锻炼，可以改变年轻人的昼夜节律。类似的研究还没有在老年人中进行过。本研究考察了老年人（n = 8； 55-73岁）和年轻人（n = 8； 20-32岁）单次3小时低强度夜间运动的昼夜节律延迟效应。在每个被试习惯性睡眠时间的开始，被试在对照条件下的相应时间坐在昏暗灯光下的椅子上。暗光褪黑激素起效（DLMO）被用作昼夜节律阶段标记。与对照组相比，训练后的DLMO阶段延迟更大。平均而言，老年人和年轻人在运动和控制条件下的相移差异相似，这表明运动对昼夜节律系统的相移效应在老年人中保持不变。因此，锻炼可能是一种有用的治疗方法，可以帮助调整老年人和年轻人的昼夜节律。
Exercise can phase shift the circadian rhythms of young adults if performed at the right time of day. Similar research has not been done in older adults. This study examined the circadian phase-delaying effects of a single 3-h bout of low-intensity nocturnal exercise in older (n = 8; 55-73 yr old) vs. young (n = 8; 20-32 yr old) adults. The exercise occurred at the beginning of each subject's habitual sleep time, and subjects sat in a chair in dim light during the corresponding time in the control condition. The dim-light melatonin onset ( DLMO) was used as the circadian phase marker. The DLMO phase delayed more after the exercise than after the control condition. On average, the difference in phase shift between the exercise and control conditions was similar for older and young subjects, demonstrating that the phase-shifting effects of exercise on the circadian system are preserved in older adults. Therefore, exercise may potentially be a useful treatment to help adjust circadian rhythms in older and young adults.