Measuring the impact of MS on walking ability - The 12-Item MS Walking Scale (MSWS-12)
Measuring the impact of MS on walking ability - The 12-Item MS Walking Scale (MSWS-12)
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DOI：
10.1212/wnl.60.1.31
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发表时间：
2003-01-14
期刊：
影响因子：
9.9
通讯作者：
Thompson, AJ
中科院分区：
文献类型：
--
作者：
Hobart, JC;Riazi, A;Thompson, AJ
目的：方法：12项描述MS对行走的影响（12项MS行走量表[MSWS-12]），从30例患者访谈，专家意见和文献综述中产生。初步的心理测量评价（数据质量，缩放假设，可接受性，可靠性，有效性）进行了602人从MS社会成员数据库中产生的数据。进一步的心理评估（包括综合效度评估，反应性和相对效率）进行了两个医院为基础的样本：人与原发性进展MS（PPMS; n = 78）和复发的人承认IV类固醇治疗（n = 54）。结果如下：在所有样本中，缺失数据较低（小于或等于3.8%），项目重测重现性较高（大于或等于0.78），满足标度假设，信度较高（大于或等于0.94）。MSWS-12和其他量表之间的相关性与先验假设一致。MSWS-12（相对效率= 1.0）比多发性硬化症活动度量表的功能评估更敏感（0.72）、36项简明健康调查身体功能量表（0.33）、扩展残疾状态量表（0.03）、25英尺计时步行测试（0.44）和盖伊神经功能障碍量表下肢残疾项目（0.10）。结论：MSWS-12满足标准标准，是MS对行走影响的可靠有效的基于患者的测量方法。在这些样本中，MSWS-12比其他基于步行的量表更具响应性。
Objective: To develop a patient-based measure of walking ability in MS. Methods: Twelve items describing the impact of MS on walking (12-Item MS Walking Scale [MSWS-12]) were generated from 30 patient interviews, expert opinion, and literature review. Preliminary psychometric evaluation (data quality, scaling assumptions, acceptability, reliability, validity) was undertaken in the data generated by 602 people from the MS Society membership database. Further psychometric evaluation (including comprehensive validity assessment, responsiveness, and relative efficiency) was conducted in two hospital-based samples: people with primary progressive MS (PPMS; n = 78) and people with relapses admitted for IV steroid treatment (n = 54). Results: In all samples, missing data were low (less than or equal to3.8%), item test-retest reproducibility was high (greater than or equal to0.78), scaling assumptions were satisfied, and reliability was high (greater than or equal to0.94). Correlations between the MSWS-12 and other scales were consistent with a priori hypotheses. The MSWS-12 (relative efficiency = 1.0) was more responsive than the Functional Assessment of Multiple Sclerosis mobility scale (0.72), the 36-Item Short Form Health Survey physical functioning scale (0.33), the Expanded Disability Status Scale (0.03), the 25-ft Timed Walk Test (0.44), and Guy's Neurologic Disability Scale lower limb disability item (0.10). Conclusions: The MSWS-12 satisfies standard criteria as a reliable and valid patient-based measure of the impact of MS on walking. In these samples, the MSWS-12 was more responsive than other walking-based scales.