A Toggle Nanoswitch Alternately Controlling Two Catalytic Reactions
A Toggle Nanoswitch Alternately Controlling Two Catalytic Reactions
复制标题
DOI：
10.1002/anie.201408457
复制
发表时间：
2014-12-15
影响因子：
16.6
通讯作者：
Schmittel, Michael
中科院分区：
文献类型：
--
作者：
De, Soumen;Pramanik, Susnata;Schmittel, Michael
通过交替加入2-二茂铁基-1，10-菲咯啉（2）和铜（I）离子实现了三角形纳米开关[Cu（1）]（+）的两种状态之间的可逆切换。这两种切换状态以完全无干扰的方式调节两种不同催化剂哌啶和[Cu（2）]（+）的结合和释放，并允许两个正交催化过程的交替开/关切换。在切换状态I中，哌啶从纳米开关释放并催化4-硝基苯甲醛和丙二酸二乙酯之间的Knoevenagel加成（ON-1和OFF-2），而在状态II中，释放的[Cu（2）]（+）催化4-硝基-苯乙炔和苄基叠氮化物之间的点击反应（OFF-1和ON-2）。在向（OFF-1和ON-2）状态添加一当量的2时，两个催化活性过程都被关闭（OFF-1和OFF-2）。
Reversible switching between two states of the triangular nanoswitch [Cu(1)](+) was accomplished by alternate addition of 2-ferrocenyl-1,10-phenanthroline (2) and copper(I) ions. The two switching states regulate the binding and release of two distinct catalysts, piperidine and [Cu(2)](+), in a fully interference-free manner and allow alternating on/off switching of two orthogonal catalytic processes. In switching state I, piperidine is released from the nanoswitch and catalyzes a Knoevenagel addition between 4-nitrobenzaldehyde and diethyl malonate (ON-1 and OFF-2), while in state II the released [Cu(2)](+) catalyzes a click reaction between 4-nitro-phenylacetylene and benzylazide (OFF-1 and ON-2). Upon addition of one equivalent of 2 to the (OFF-1 and ON-2)-state, both catalytically active processes are shut down (OFF-1 and OFF-2).