Elastography of breast lesions: Initial clinical results
Elastography of breast lesions: Initial clinical results
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DOI：
10.1148/radiology.202.1.8988195
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发表时间：
1997-01-01
期刊：
影响因子：
19.7
通讯作者：
Pennanen, MF
中科院分区：
文献类型：
--
作者：
Garra, BS;Cespedes, EI;Pennanen, MF
目的：确定各种乳腺病变在弹性图上的表现，探讨弹性图在乳腺病变诊断中的潜力。材料和方法：对46例乳腺病变进行弹性成像检查。患者对所有病变进行活检或抽吸，发现15个纤维腺瘤，12个癌，6个纤维囊性结节和13个其他病变。弹性图由使用5 mhz线性阵列换能器收集的射频数据生成。弹性图和相应的超声图由单个观察者评估病变的可视化、相对亮度、边缘定义和规律性。记录每次影像学检查和活检时病变的大小并进行比较。结果：软组织如脂肪在弹性图上呈亮区。实组织，包括实质组织、癌组织和其他肿块，颜色变深。肿瘤颜色比纤维腺瘤深（P < 0.005），弹性图比超声图大得多。73%的纤维腺瘤和56%的实体性良性病变可通过病变亮度和大小差异与癌症区分。一些在超声图上表现为阴影区域的癌症在弹性图上表现为离散的肿块。结论：弹性成像在超声图上阴影区域的评估中具有潜在的应用价值。它也可能有助于区分良性和恶性肿块。
PURPOSE: To determine the appearance of various breast lesions on elastograms and to explore the potential of elastography in the diagnosis of breast lesions.MATERIALS AND METHODS: A total of 46 breast lesions were examined with elastography. Patients underwent biopsy or aspiration of all lesions, revealing 15 fibroadenomas, 12 carcinomas, six fibrocystic nodules, and 13 other lesions. The elastogram was generated from radio-frequency data collected with use of a 5-MHz linear-array transducer. The elastogram and corresponding sonogram were evaluated by a single observer for lesion visualization, relative brightness, and margin definition and regularity. The sizes of the lesions at each imaging examination and at biopsy were recorded and compared.RESULTS: Softer tissues such as fat appear as bright areas on elastograms. Firm tissues, including parenchyma, cancers, and other masses, appear darker. The cancers were statistically significantly darker than fibroadenomas (P < .005) and substantially larger on the elastogram than on the sonogram. Seventy-three percent of fibroadenomas and 56% of solid benign lesions could be distinguished from cancers by using lesion brightness and size difference. Some cancers that appeared as areas of shadowing on sonograms appeared as discrete masses on elastograms.CONCLUSION: Elastography has the potential to be useful in the evaluation of areas of shadowing on the sonogram. It also may be helpful in the distinction of benign from malignant masses.