Electrochemical impedance study of the interaction of metal ions with unlabeled PNA

Electrochemical impedance study of the interaction of metal ions with unlabeled PNA
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金属离子与未标记 PNA 相互作用的电化学阻抗研究

DOI:
10.1039/c0cc00986e
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发表时间:
2010-01-01
影响因子:
4.9
通讯作者:
Kraatz, Heinz-Bernhard
Kraatz, Heinz-Bernhard
中科院分区:
化学2区
文献类型:
--
作者:
Gao, Lan;Li, Congjuan;Kraatz, Heinz-Bernhard

文献摘要

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利用电化学阻抗谱(EIS)研究了金属离子Mg2+、Zn2+、Ni2+和Co2+与肽核酸(PNAs)薄膜的相互作用,结果表明,除Mg2+与主链和核碱基的相互作用为主外,Zn2+、Ni2+和Co2+与PNA薄膜的相互作用均有利。
The interactions of the metal ions Mg2+, Zn2+, Ni2+, and Co2+ with thin films of peptide nucleic acids (PNAs) were studied by electrochemical impedance spectroscopy (EIS), and the results show that Zn2+, Ni2+ and Co2+ interacted favorably with the PNA film involving the backbone and the nucleobases with the exception of Mg2+ for which the interaction with the backbone appears to be dominant.