Copper-Catalyzed N-H Insertion and Oxidative Aromatization Cascade: Facile Synthesis of 2-Arylaminophenols
Copper-Catalyzed N-H Insertion and Oxidative Aromatization Cascade: Facile Synthesis of 2-Arylaminophenols
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铜催化 N-H 插入和氧化芳构化级联：2-芳基氨基苯酚的简便合成
DOI：
10.1002/asia.201402080
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发表时间：
2014-06-01
影响因子：
4.1
通讯作者：
Sun, Jiangtao
中科院分区：
文献类型：
--
作者：
Ding, Dong;Lv, Xiaobing;Sun, Jiangtao
发展了铜催化的N-H插入-氧化芳构化级联反应。2-芳基氨基苯酚已从重氮底物中以中等到高的产率制备。此外，这种新建立的方法允许有效地获得天然1-氧化咔唑生物碱，如甘氨唑碱和九里香碱A。
A copper-catalyzed cascade reaction of N-H insertion and oxidative aromatization has been developed. 2-Arylaminophenols have been prepared in moderate to high yields from the diazo substrates. Moreover, this newly established methodology allows efficient access to natural 1-oxygenated carbazole alkaloids, such as glycozolicine and murrayafolineA.