A new biocompatible coating layer applied on titanium substrates using a modified zinc phosphatizing method
A new biocompatible coating layer applied on titanium substrates using a modified zinc phosphatizing method
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DOI：
10.1016/j.surfcoat.2011.09.064
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发表时间：
2012-01
影响因子：
5.4
通讯作者：
A. Valanezhad;K. Tsuru;Michito Maruta;Giichiro Kawachi;S. Matsuya;K. Ishikawa
中科院分区：
文献类型：
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作者：
A. Valanezhad;K. Tsuru;Michito Maruta;Giichiro Kawachi;S. Matsuya;K. Ishikawa
在钛基体上制备了一种新型的生物相容性涂层。通过在酸性磷酸锌溶液中在250°C下水热处理8小时或更长时间。结晶涂层的元素分析表明存在Zn、Ti和P，其原子比近似为0.27：0.86：1。X-射线衍射分析表明，涂层为类四斜方尖晶石结构（空间群为I41/amd），晶格常数为a=0.5173nm，c=1.3017nm，是一种新的磷酸锌钛（Ti-Zn-PO 4）相。在250°C下保温10 h制备的Ti-Zn-PO 4涂层与基体的界面断裂强度高于实测结合强度（48.3±9.2MPa）。体外细胞实验结果表明，Ti-Zn-PO 4涂层的细胞增殖效果明显好于未涂层的钛基体。因此，我们得出结论，Ti-Zn-PO 4涂层可能用于生物医学应用，如钛植入物。
A new biocompatible coating layer was successfully prepared on titanium (Ti) substrate. by hydrothermal treatment in an acidic zinc phosphate solution at 250°C for 8h or longer time. Elemental analysis of the crystalline coating layer showed the existence of Zn, Ti and P with an approximate atomic ratio of 0.27:0.86:1. From X-ray diffractometry, the crystalline coating structure could be indexed as tetragonal lipscombite-like structure (space group, I41/amd) with lattice parameters of a=0.5173nm and c=1.3017nm and was identified as a new zinc titanium phosphate (Ti–Zn–PO4) phase. The interfacial fracture strength between substrate and Ti–Zn–PO4coating layer prepared at 250°C for 10h was higher than the measured adhesive strength value (48.3±9.2MPa). In vitro cell study indicated that cell proliferation results for Ti–Zn–PO4layer were much better than those for non-coated Ti substrates. We therefore concluded that the Ti–Zn–PO4coating might be useful for biomedical applications such as Ti implants.