Accurate quantification of tio2 nanoparticles collected on air filters using a microwave-assisted acid digestion method.
Accurate quantification of tio2 nanoparticles collected on air filters using a microwave-assisted acid digestion method.
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DOI：
10.1080/15459624.2015.1072278
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发表时间：
2016
影响因子：
2
通讯作者：
Peters TM
中科院分区：
文献类型：
--
作者：
Mudunkotuwa IA;Anthony TR;Grassian VH;Peters TM
二氧化钛（TiO 2）颗粒，包括直径小于100 nm的纳米颗粒，广泛用于消费品中。在2011年的一份最新情报公报中，美国国家职业安全与健康研究所（NIOSH）推荐了评估工人暴露于微细和超细TiO 2颗粒的方法，以及这些颗粒的相关职业暴露限值。然而，这些推荐的暴露评估方法遇到了一些挑战和问题，包括使用酸消化然后使用电感耦合等离子体发射光谱法（ICP-OES）对空气过滤器上收集的二氧化钛进行准确定量。具体而言，推荐的消化方法包括使用化学品，如高氯酸，由于高度腐蚀性和氧化性，大多数认可的工业卫生实验室通常无法使用高氯酸。通常使用的其他替代方法涉及使用硝酸或硝酸和硫酸的组合，其产生非常差的二氧化钛回收率。因此，鉴于目前的科学状况，显然需要一种新的方法来进行接触评估。在目前的研究中，微波辅助酸消化方法已被专门设计，以提高回收率的二氧化钛纳米粒子的定量分析，使用电感耦合等离子体发射光谱。通过改变几个变量，包括使用的酸，消化时间，和温度，确定了最佳消化条件。因此，使用浓硫酸和硝酸（2：1 v/v）的210°C的优化消化温度导致TiO 2的回收率>90%。该方法预计将提供一个更准确的量化工作场所环境中的空气中的二氧化钛颗粒。
Titanium dioxide (TiO2) particles, including nanoparticles with diameters smaller than 100 nm, are used extensively in consumer products. In a 2011 current intelligence bulletin, the National Institute of Occupational Safety and Health (NIOSH) recommended methods to assess worker exposures to fine and ultrafine TiO2 particles and associated occupational exposure limits for these particles. However, there are several challenges and problems encountered with these recommended exposure assessment methods involving the accurate quantitation of titanium dioxide collected on air filters using acid digestion followed by inductively coupled plasma optical emission spectroscopy (ICP-OES). Specifically, recommended digestion methods include the use of chemicals, such as perchloric acid, which are typically unavailable in most accredited industrial hygiene laboratories due to highly corrosive and oxidizing properties. Other alternative methods that are used typically involve the use of nitric acid or combination of nitric acid and sulfuric acid, which yield very poor recoveries for titanium dioxide. Therefore, given the current state of the science, it is clear that a new method is needed for exposure assessment. In this current study, a microwave-assisted acid digestion method has been specifically designed to improve the recovery of titanium in TiO2 nanoparticles for quantitative analysis using ICP-OES. The optimum digestion conditions were determined by changing several variables including the acids used, digestion time, and temperature. Consequently, the optimized digestion temperature of 210°C with concentrated sulfuric and nitric acid (2:1 v/v) resulted in a recovery of >90% for TiO2. The method is expected to provide for a more accurate quantification of airborne TiO2 particles in the workplace environment.