Mobile Phone Text Messages to Support Treatment Adherence in Adults With High Blood Pressure (SMS-Text Adherence Support [StAR]): A Single-Blind, Randomized Trial.
Mobile Phone Text Messages to Support Treatment Adherence in Adults With High Blood Pressure (SMS-Text Adherence Support [StAR]): A Single-Blind, Randomized Trial.
复制标题
手机短信以支持高血压的成年人的治疗依从性（SMS-Text依从性支持[Star]）：一项单盲，随机试验。
DOI：
10.1161/circulationaha.115.017530
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发表时间：
2016-02-09
期刊：
影响因子：
37.8
通讯作者：
Levitt N
中科院分区：
文献类型：
--
作者：
Bobrow K;Farmer AJ;Springer D;Shanyinde M;Yu LM;Brennan T;Rayner B;Namane M;Steyn K;Tarassenko L;Levitt N
我们评估了通过手机短信系统（SMS）短信提供的自动治疗依从性支持对血压的影响。在南非进行的这项实用的单盲、三臂随机试验（星星）中，接受高血压治疗的患者以1：1：1的比例被随机分配到仅提供信息或交互式SMS短信或常规护理组。主要结局是使用经验证的血压测量装置测量的12个月时收缩压相对于基线的变化。所有试验工作人员均对治疗分配设盲。2012年6月26日至2012年11月23日期间，1372名参与者被随机分配接受仅提供信息的短信（n=457），交互式短信（n=458）或常规护理（n=457）。1256例（92%）参与者的主要结局数据可用。在12个月时，与常规治疗相比，收缩压的平均调整变化（95% CI）为-2.2 mmHg（-4.4至-0.04）（仅提供信息的SMS）和-1.6 mmHg（-3.7至0.6）（交互式SMS）。与常规护理相比，血压<140/90 mm Hg的参与者比例的比值比（95% CI）为仅信息消息1.42（1.03至1.95）和交互式消息1.41（1.02至1.95）。在这项通过短信在普通门诊高血压成人人群中提供自动依从性支持计划的随机试验中，我们发现12个月时收缩压控制与常规护理相比略有下降。没有证据表明互动干预增加了这种效果。ClinicalTrials.gov.标识符：南非国家临床试验注册编号（SANCTR DOH-27-1212-386）;泛非试验注册（PACTR 201411000724141）。
We assessed the effect of automated treatment adherence support delivered via mobile-phone short message system (SMS) text-messages on blood pressure. In this pragmatic single-blind, three-arm randomized trial (StAR), undertaken in South Africa, patients treated for high blood pressure were randomly allocated in a 1:1:1 ratio to information-only or interactive SMS text-messaging, or usual care. The primary outcome was change in systolic blood pressure at 12-months from baseline measured with a validated oscillometric device. All trial staff were masked to treatment allocation. Analyses were intention to treat. Between June 26, 2012 and November 23, 2012, 1372 participants were randomized to receive information-only SMS text-messages (n=457), interactive SMS text-messages (n=458), or usual care (n=457). Primary outcome data were available for 1256 (92%) participants. At 12-months, the mean adjusted change (95% CI) in systolic blood pressure compared to usual care was −2.2 mm Hg (−4.4 to −0.04) with information-only SMS and −1.6 mm Hg (−3.7 to 0.6) with interactive SMS. Odds ratios (95% CI) for the proportion of participants with a blood pressure <140/90mm Hg were for information-only messaging 1.42 (1.03 to 1.95) and for interactive messaging 1.41 (1.02 to 1.95) compared to usual care. In this randomized trial of an automated adherence support program delivered by SMS text-message in a general outpatient population of adults with high blood pressure, we found a small, reduction in systolic blood pressure control compared to usual care at 12-months. There was no evidence that an interactive intervention increased this effect. ClinicalTrials.gov. Identifier: South African National Clinical Trials Register number (SANCTR DOH-27-1212-386); Pan Africa Trial Register (PACTR201411000724141).