MULTICHANNEL BIOMAGNETIC SYSTEM FOR STUDY OF ELECTRICAL-ACTIVITY IN THE BRAIN AND HEART
MULTICHANNEL BIOMAGNETIC SYSTEM FOR STUDY OF ELECTRICAL-ACTIVITY IN THE BRAIN AND HEART
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DOI：
10.1148/radiology.176.3.2389043
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发表时间：
1990-09-01
期刊：
影响因子：
19.7
通讯作者：
WIRTH, A
中科院分区：
文献类型：
--
作者：
SCHNEIDER, S;HOENIG, E;WIRTH, A
作者设计了一个多通道系统，用于对大脑和心脏产生的极弱磁场进行无创测量。它使用了一个由37个超导磁场感应线圈组成的平面阵列，这些线圈与复杂的超导量子干涉装置相连。为了防止外部电磁场的干扰，系统在屏蔽室内运行。完整的连贯数据集，甚至来自自发事件，都可以被记录下来。通过模拟测量和诱发反应研究来评估系统性能。获得了几毫米的空间分辨率和一毫秒的时间分辨率。部分癫痫患者的初步结果和心脏传导途径的调查表明，生物磁学现在已经准备好进行系统的临床评估。通过在三维数字磁共振图像中突出生物磁学局部电活动，可以方便地解释测量结果。
The authors designed a multichannel system for noninvasive measurement of the extremely weak magnetic fields generated by the brain and the heart. It uses a flat array of 37 superconducting magnetic field-sensing coils connectd to sophisticated superconducting quantum interference devices. To prevent interference from external electromagnetic fields, the system is operated inside a shielded room. Complete sets of coherent data, even from spontaneous events, can be recorded. System performance was evaluated with phantom measurements and evoked-response studies. A spatial resolution of a few millimeters and a temporal resolution of a millisecond were obtained. First results in patients with partial epilepsy and investigations of the cardiac conductive pathway indicate that biomagnetism is now ready for a systematic clinical evaluation. Interpretation of measurements was facilitated by highlighting biomagnetically localized electrical activity in three-dimensional digital magnetic resonsance images.