Characterization of the calcaneal fat pad in diabetic and nondiabetic patients using magnetic resonance imaging
Characterization of the calcaneal fat pad in diabetic and nondiabetic patients using magnetic resonance imaging
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DOI：
10.1016/s0730-725x(99)00019-3
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发表时间：
1999-07-01
影响因子：
2.5
通讯作者：
Hardy, PA
中科院分区：
文献类型：
--
作者：
Kao, PF;Davis, BL;Hardy, PA
众所周知，糖尿病患者足部溃疡的发生率很高。本研究的目的是确定磁共振（MR）成像是否可以检测到糖尿病足跟骨脂肪垫组成的变化。从截肢标本（8例来自糖尿病患者，8例来自非糖尿病患者）以及年龄匹配的糖尿病和对照受试者（每组4例受试者）体内收集MR数据。三种类型的图像采集：自旋晶格（T-1），自旋-自旋（T-2），磁化转移（M-T），在体外结果显示，在T-1，T-2，和MT参数的两个疾病组之间的统计学上的显着差异。在活体受试者的研究中显示了相同的趋势，但差异无统计学意义。这些差异被认为是由于糖尿病进展导致的组织组成的变化而引起的。(C)1999 Elsevier Science Inc.
It is well known that diabetic patients have a high incidence of foot ulceration. The purpose of this study was to determine whether magnetic resonance (MR) imaging can detect changes in the composition of the calcaneal fat pad in diabetic feet. MR data were collected in vitro from amputated specimens (eight from diabetic patients and eight from non-diabetic patients) as well as in vivo from age-matched diabetic and control subjects (four subjects each group.) Three types of images were acquired: spin lattice (T-1), spin-spin (T-2), and magnetization transfer (M-T), The in vitro results showed statistically significant differences in the T-1, T-2, and MT parameters between the two disease groups. The same trends were shown in the study of live subjects but the differences were not statistically significant. The differences are believed to arise from changes in the composition of the tissues as a result of the progression of diabetes. (C) 1999 Elsevier Science Inc.