Simultaneous determination of dopamine and uric acid using layer-by-layer graphene and chitosan assembled multilayer films
Simultaneous determination of dopamine and uric acid using layer-by-layer graphene and chitosan assembled multilayer films
复制标题
层层石墨烯和壳聚糖组装多层膜同时测定多巴胺和尿酸
DOI：
10.1016/j.talanta.2013.09.023
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发表时间：
2013-12-15
期刊：
影响因子：
6.1
通讯作者：
Wu, Lanju
中科院分区：
文献类型：
--
作者：
Weng, Xuexiang;Cao, Qingxue;Wu, Lanju
采用分层组装技术在玻碳电极上制备了石墨烯（Gr）和壳聚糖（CS）多层膜。利用循环伏安法（CV）、电化学阻抗谱（EIS）和扫描电镜（SEM）对制备的电化学传感器进行了表征，建立了同时测定多巴胺（DA）和尿酸（UA）的电化学传感器。LBL组装电极对DA和UA的氧化表现出良好的电催化活性。此外，自组装电极对DA和UA的检测具有良好的传感性能，在0.1 μ M ~ 140 μ M和1.0 μ M ~ 125 μ M的线性范围内，基于S/N=3的检测限分别低至0.05 μ M和0.1 μ M。(C) 2013 Elsevier B.V.版权所有
Multilayer films containing graphene (Gr) and chitosan (CS) were prepared on glassy carbon electrodes with layer-by-layer (LBL) assembly technique. After being characterized with cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and scanning electron microscopy (SEM), the electrochemical sensor based on the resulted films was developed to simultaneously determine dopamine (DA) and uric acid (UA). The LBL assembled electrode showed excellent electrocatalytic activity towards the oxidation of DA and UA. In addition, the self-assembly electrode possessed an excellent sensing performance for detection of DA and UA with a linear range from 0.1 mu M to 140 mu M and from 1.0 mu M to 125 mu M with the detection limit as low as 0.05 mu M and 0.1 mu M based on S/N=3, respectively. (C) 2013 Elsevier B.V. All rights reserved.