Functional Neuroimaging Studies of Motor Recovery After Stroke in Adults
Functional Neuroimaging Studies of Motor Recovery After Stroke in Adults
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DOI：
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发表时间：
2003-06
期刊：
影响因子：
8.3
通讯作者：
CinziaCalautti;Jean-ClaudeBaron
中科院分区：
文献类型：
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作者：
CinziaCalautti;Jean-ClaudeBaron
背景-成人脑卒中后运动恢复的确切机制和生物学基础在很大程度上仍然未知。脑卒中后运动系统重组的功能神经影像学评估是一个有趣但具有挑战性的新研究领域。迄今为止，已经报道了一些具有挑衅性但模棱两可的发现。综述-我们介绍了功能神经影像学研究（正电子发射断层扫描或功能性MRI）的运动任务的患者恢复或仍在恢复从卒中后的运动缺陷。在简要介绍了运动系统的连通性和正常受试者的影像学表现后，回顾和讨论了有关中风患者的文献，并提出了一个通用模型。结论：横断面和纵向研究都表明，受损的成人大脑能够重组以补偿运动缺陷。而不是功能的完全替代，运动能力恢复的主要机制…
Background— The precise mechanisms of and biological basis for motor recovery after stroke in adults are still largely unknown. Reorganization of the motor system after stroke as assessed by functional neuroimaging is an intriguing but challenging new field of research. Provocative but equivocal findings have been reported to date. Summary of Review— We present an overview of functional neuroimaging studies (positron emission tomography or functional MRI) of motor tasks in patients recovered or still recovering from motor deficit after stroke. After a brief account of the connectivity of motor systems and the imaging findings in normal subjects, the literature concerning stroke patients is reviewed and discussed, and a general model is proposed. Conclusions— Both cross-sectional and longitudinal studies have demonstrated that the damaged adult brain is able to reorganize to compensate for motor deficits. Rather than a complete substitution of function, the main mechanism underlying recovery of motor abili...