Systemic treatments for women with breast cancer: outcome with relation to screening for the disease

Systemic treatments for women with breast cancer: outcome with relation to screening for the disease
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DOI:
10.1093/annonc/mdg327
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发表时间:
2003-08-01
期刊:
影响因子:
50.5
通讯作者:
Gelber, RD
Gelber, RD
中科院分区:
医学1区
文献类型:
--
作者:
Goldhirsch, A;Colleoni, M;Gelber, RD

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乳腺癌的早期发现和适当护理是目前治疗乳腺癌患者的最佳方法。在实施了乳腺癌筛查方案的国家,与乳腺癌有关的死亡率明显降低。在瑞士也观察到这种减少,该国没有国家筛查方案。虽然早期诊断无疑在降低乳腺癌死亡率方面发挥了重要作用,但这种作用的程度尚不清楚。有必要对高危妇女乳腺癌早期检测的替代成像方法和根据对治疗反应的适当标准提供的治疗方法进行量身定制的研究。
Early detection and proper care of breast cancer are currently the best available approaches to the treatment of patients with the disease. In countries with a breast cancer screening programme, there has been a demonstrated reduction in breast cancer-related mortality. Such reduction has also been observed in Switzerland, a country in which no national programme of screening is available. Although there is no doubt that early diagnosis might have had a major role in reducing breast cancer mortality the magnitude of this effect is unknown. Research with tailored approaches on alternative imaging for early detection of breast cancer in high-risk women and on treatments offered according to proper criteria of responsiveness to therapies is warranted.