CYTOLOGICAL STUDIES ON THE DEVELOPING VITREOUS AS RELATED TO THE HYALOID VESSEL SYSTEM
CYTOLOGICAL STUDIES ON THE DEVELOPING VITREOUS AS RELATED TO THE HYALOID VESSEL SYSTEM
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DOI：
10.1007/bf00413534
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发表时间：
1980-01-01
期刊：
影响因子：
--
通讯作者：
OZANICS, V
中科院分区：
文献类型：
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作者：
BALAZS, EA;TOTH, LZ;OZANICS, V
哺乳动物玻璃体细胞群的胚胎发育可追溯到2个来源：眼原基的未分化间充质细胞和骨髓的原始网状细胞。未分化的间充质细胞以两种方式侵入未来的玻璃体腔：通过视杯边缘和透镜原基之间的环形开口，以及通过开放的胚胎裂隙。它们分化为位于视神经乳头区域的血管前细胞、成血管细胞和纤维细胞。从胎儿发育的一开始，另一种间充质来源的阿米巴样细胞通过玻璃体血管进入玻璃体;这些单核细胞样细胞分化为透明细胞，并在靠近视网膜和锯齿缘的皮质玻璃体中占据明确的区域。γ-辐射（600拉德）的新生兔和猫的数量减少迁移变形细胞在他们的玻璃体; 24小时后，他们被取代的单核细胞从玻璃体血管。
The embryonic development of the mammalian vitreous cell population was traced to 2 sources: the undifferentiated mesenchymal cells of the eye primordium and the primitive reticular cells of the bone marrow. Undifferentiated mesenchymal cells invade the future vitreous space in 2 ways: through the annular opening between the rim of the optic cup and the lens primordium, and through the open embryonic fissure. They differentiate into prevascular cells, hemangioblasts and fibrocytes located in the area of the optic nerve head. From the very beginning of fetal development, another ameboid-type cell of mesenchymal origin makes its entrance into the vitreous through the hyaloid vessels; these monocyte-like cells differentiate into hyalocytes and populate a well-defined area of the cortical vitreous close to the retina and to the ora serrata. .gamma.-Irradiation (600 rads) of newly born rabbits and cats decreases the number of migrating amebocytes in their vitreous; 24 h later they are replaced by monocytes from the hyaloid vessels.