Tuberculosis Treatment Monitoring by Video Directly Observed Therapy in 5 Health Districts, California, USA
Tuberculosis Treatment Monitoring by Video Directly Observed Therapy in 5 Health Districts, California, USA
复制标题
DOI：
10.3201/eid2410.180459
复制
发表时间：
2018-10-01
影响因子：
11.8
通讯作者：
Raab, Fredric
中科院分区：
文献类型：
--
作者：
Garfein, Richard S.;Liu, Lin;Raab, Fredric
我们评估了美国加利福尼亚州 5 个卫生区用于监测结核病治疗的视频直接观察疗法 (VDOT)，比较了使用 VDOT 的 174 名患者和使用现场直接观察疗法 (DOT) 的 159 名患者之间的依从性。多变量线性回归分析确定了参与者报告的社会人口统计学、风险行为和与依从性相关的治疗经验。参与者年龄中位数为 44 岁（范围 18-87 岁）； 61%的参与者是男性。 VDOT 参与者中观察到的预期剂量中位数 (FEDO) 高于接受 DOT 的患者 (66.4% [IQR 55.1%-89.3%]) (93.0% [四分位距 (IQR) 83.4%-97.1%])。大多数参与者 (96%) 会向其他人推荐 VDOT； 90% 的人更喜欢 VDOT 而不是 DOT。较低的 FEDO 与美国或墨西哥出生、较短的 VDOT 持续时间、发现 VDOT 困难、经常外出时服用药物以及存在视频录制问题独立相关（p
We assessed video directly observed therapy (VDOT) for monitoring tuberculosis treatment in 5 health districts in California, USA, to compare adherence between 174 patients using VDOT and 159 patients using in-person directly observed therapy (DOT). Multivariable linear regression analyses identified participant-reported sociodemographics, risk behaviors, and treatment experience associated with adherence. Median participant age was 44 (range 18-87) years; 61% of participants were male. Median fraction of expected doses observed (FEDO) among VDOT participants was higher (93.0% [interquartile range (IQR) 83.4%-97.1%]) than among patients receiving DOT (66.4% [IQR 55.1%-89.3%]). Most participants (96%) would recommend VDOT to others; 90% preferred VDOT over DOT. Lower FEDO was independently associated with US or Mexico birth, shorter VDOT duration, finding VDOT difficult, frequently taking medications while away from home, and having video-recording problems (p