Factors associated with adolescent initiation of injection drug use
Factors associated with adolescent initiation of injection drug use
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DOI：
10.1093/phr/116.s1.136
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发表时间：
2001-01-01
影响因子：
3.3
通讯作者：
Strathdee, SA
中科院分区：
文献类型：
--
作者：
Fuller, CM;Vlahov, D;Strathdee, SA
Objective.本研究的目的是评估在何种程度上人口统计学，性，和非注射吸毒的做法预测青少年开始注射吸毒。Street招募了巴尔的摩（马里兰州）15-30岁的注射吸毒者，他们在研究入组后5年内开始注射，并完成了一份问卷，其中包括开始注射前5年的逐年病史。使用逻辑回归分析确定与青春期（小于或等于21岁）和青年期（> 21岁）开始性行为相关的因素。在226名参与者中，大多数是女性（61%）和非洲裔美国人（64%）。参与者的中位年龄为25岁;开始注射时的中位年龄为23岁。在多变量分析中，与青少年启动显着相关的因素包括非裔美国人以外的种族，以及启动注射前的做法，包括使用避孕套，缺乏可卡因的使用，启动前仅吸食可卡因，吸食大麻。在开始注射前，青少年开始使用非法药物的持续时间也较短。短期非注射毒品使用，特别是纯可卡因吸烟，与青少年开始注射毒品使用有关。有必要针对年轻吸毒者这一高风险群体开展早期预防工作，以推迟或预防注射吸毒的开始。
Objective. The purpose of this study was to evaluate the extent to which demographic, sexual, and non-injection drug use practices predict adolescent initiation of injection drug use.Methods. Street recruited injection drug users 15-30 years of age in Baltimore, Maryland, who initiated injection within five years of study enrollment, completed a questionnaire that included a year-by-year history regarding the five years prior to initiation of injection. Factors associated with initiation during adolescence (less than or equal to 21 years of age) versus young adulthood (> 21) were determined using logistic regression.Results. Of 226 participants, most were female (61%) and African American (64%). Median age of participants was 25; median age at initiation of injection was 23. Factors significantly associated with adolescent initiation in multivariate analysis included race other than African American, and practices prior to initiating injection including condom use, lack of cocaine use, exclusive crack smoking just prior to initiation, and smoking marijuana. Adolescent initiates also had shorter durations of illicit drug use prior to initiating injection.Conclusion. Short-term non-injection drug use, particularly exclusive crack smoking, was associated with adolescent initiation of injection drug use. Early prevention efforts targeting this high-risk group of younger drug users are warranted in order to delay or prevent onset of injection drug use.